Andrea L. Ferris

Frederick National Laboratory for Cancer Research — United States

Immunology and Microbiology · Life Sciences

27h-index5.8kcitations44works0.02yr avg
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Research Topics

HIV Research and Treatment(22), HIV/AIDS drug development and treatment(19), Virus-based gene therapy research(13), CRISPR and Genetic Engineering(8), HIV/AIDS Research and Interventions(7)

Publications44 total

INSTIs and NNRTIs Potently Inhibit HIV-1 Polypurine Tract Mutants in a Single Round Infection Assay
Viruses·2021· 14 citedOpen Access
A Combination of Amino Acid Mutations Leads to Resistance to Multiple Nucleoside Analogs in Reverse Transcriptases from HIV-1 Subtypes B and C
Antimicrobial Agents and Chemotherapy·2021· 3 citedOpen Access
Downregulation of <i>Grem1</i> expression in the distal limb mesoderm is a necessary precondition for phalanx development
Developmental Dynamics·2021· 6 citedOpen Access
Clonal expansion of SIV-infected cells in macaques on antiretroviral therapy is similar to that of HIV-infected cells in humans
PLoS Pathogens·2019· 40 citedOpen Access
Reprogramming human T cell function and specificity with non-viral genome targeting
Nature·2018· 819 citedOpen Access
18 Expanded clones in SIV-infected macaques on antiretroviral therapy recapitulate key features of expanded clones in HIV infection: implications for evaluation of ‘HIV cure’ interventions
Journal of Virus Eradication·2017Open Access
B-108 Specific HIV integration sites are linked to clonal expansion and persistence of infected cells
JAIDS Journal of Acquired Immune Deficiency Syndromes·2016· 296 cited
Clones of SIV-infected cells are present in spleen and lymph nodes in rhesus macaques
Journal of Virus Eradication·2015· 2 citedOpen Access
LEDGF/p75 interacts with mRNA splicing factors and targets HIV-1 integration to highly spliced genes
Genes & Development·2015· 112 citedOpen Access
The Integrator complex controls the termination of transcription at diverse classes of gene targets
Cell Research·2015· 157 citedOpen Access
Specific HIV integration sites are linked to clonal expansion and persistence of infected cells
Science·2014· 878 citedOpen Access
Mutations in HIV-1 Reverse Transcriptase Affect the Errors Made in a Single Cycle of Viral Replication
Journal of Virology·2014· 56 citedOpen Access
Enhancers Are Major Targets for Murine Leukemia Virus Vector Integration
Journal of Virology·2014· 106 citedOpen Access
A Homology Model of HIV-1 Integrase and Analysis of Mutations Designed to Test the Model
Journal of Molecular Biology·2013· 47 citedOpen Access
H3K4me3 Interactions with TAF3 Regulate Preinitiation Complex Assembly and Selective Gene Activation
Cell·2013· 465 citedOpen Access
Differential Effects of Human Immunodeficiency Virus Type 1 Capsid and Cellular Factors Nucleoporin 153 and LEDGF/p75 on the Efficiency and Specificity of Viral DNA Integration
Journal of Virology·2012· 121 citedOpen Access
HRP2 determines the efficiency and specificity of HIV-1 integration in LEDGF/p75 knockout cells but does not contribute to the antiviral activity of a potent LEDGF/p75-binding site integrase inhibitor
Nucleic Acids Research·2012· 99 citedOpen Access
The RCAS/TVA Somatic Gene Transfer Method in Modeling Human Cancer
2011· 9 cited
Nature, Position, and Frequency of Mutations Made in a Single Cycle of HIV-1 Replication
Journal of Virology·2010· 275 citedOpen Access
Lens epithelium-derived growth factor fusion proteins redirect HIV-1 DNA integration
Proceedings of the National Academy of Sciences·2010· 143 citedOpen Access
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Frequent Co-authors

Stephen H. Hughes(33), Xiaolin Wu(12), Eddy Arnold(6), Amnon Hizi(5), Paul L. Boyer(5), Brian Storrie(5), Jingqiong Hu(5), Cynthia E. Dunbar(5), Arthur D. Clark(4), Wei Shao(4), Steven J. Smith(4), Robert E. Donahue(4), Alfredo Jacobo‐Molina(3), Raymond G. Nanni(3), Roger Williams(3), S H Hughes(3), Frank Maldarelli(3), John M. Coffin(3), Patrick K. Clark(3), Alan Engelman(3)