Paulo H. Godoi

Materials Science · Physical Sciences

16h-index790citations58works1.32yr avg
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Research Topics

Crystallization and Solubility Studies(7), X-ray Diffraction in Crystallography(7), Computational Drug Discovery Methods(6), Protein Kinase Regulation and GTPase Signaling(5), Cancer-related Molecular Pathways(5)

Publications58 total

Identification and Optimization of 4‐Anilinoquinolines as Inhibitors of Cyclin G Associated Kinase
UNC Libraries·2025Open Access
Imidazo[1,2-b]pyridazines as inhibitors of DYRK kinases
European Journal of Medicinal Chemistry·2024· 4 citedOpen Access
Imidazo[1,2-B]Pyridazines as Inhibitors of DYRK Kinases
SSRN Electronic Journal·2024Open Access
Discovery of pyrazolo[3,4-d]pyrimidines as novel mitogen-activated protein kinase kinase 3 (MKK3) inhibitors
Bioorganic & Medicinal Chemistry·2023· 3 citedOpen Access
Discovery of novel benzothiophene derivatives as potent and narrow spectrum inhibitors of DYRK1A and DYRK1B
Bioorganic & Medicinal Chemistry Letters·2022· 3 citedOpen Access
Discovery and Characterization of Selective and Ligand-Efficient DYRK Inhibitors
Journal of Medicinal Chemistry·2021· 20 citedOpen Access
Structural characterization of human Vaccinia-Related Kinases (VRK) bound to small-molecule inhibitors identifies different P-loop conformations
UNC Libraries·2020Open Access
The PRP4K Kinase protein overexpression, production, purification and crystallization
Resumos do...·2019Open Access
Binding and structural analyses of potent inhibitors of the human Ca2+/calmodulin dependent protein kinase kinase 2 (CAMKK2) identified from a collection of commercially-available kinase inhibitors
Scientific Reports·2019· 24 citedOpen Access
Validation of the protein kinase <i>Pf</i> CLK3 as a multistage cross-species malarial drug target
Science·2019· 63 citedOpen Access
Human PRPF4B bound to benzothiophene inhibitor 224
2019
Human PIM1 bound to benzothiophene inhibitor 292
2019
Human PIM1 bound to benzothiophene inhibitor 379
2019
Human PIM1 bound to benzothiophene inhibitor 354
2019
Human PIM1 bound to benzothiophene inhibitor 213
2019
SGC-GAK-1: A Chemical Probe for Cyclin G Associated Kinase (GAK)
Journal of Medicinal Chemistry·2019· 68 citedOpen Access
Structural and binding studies of human CAMKK2 kinase domain bound to small molecule ligands
2019· 1 citedOpen Access
WNT Activates the AAK1 Kinase to Promote Clathrin-Mediated Endocytosis of LRP6 and Establish a Negative Feedback Loop
Cell Reports·2019· 95 citedOpen Access
Heparin is biocompatible and can induce differentiation of human dental pulp cells
International Endodontic Journal·2018· 9 cited
Structural Analysis of Inhibitor Binding to CAMKK1 Identifies Features Necessary for Design of Specific Inhibitors
Scientific Reports·2018· 19 citedOpen Access
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Frequent Co-authors

Jonathan M. Elkins(25), James M. Bennett(16), Rafael M. Couñago(16), William J. Zuercher(16), Carrow I. Wells(15), Timothy M. Willson(14), Christopher R. M. Asquith(12), Michael P. East(10), Tuomo Laitinen(10), Glaucius Oliva(9), Graham J. Tizzard(9), O. Gileadi(8), Katlin B. Massirer(8), Lee M. Graves(8), Gary L. Johnson(8), Ronna E. Dornsife(8), André da Silva Santiago(7), Oleg Fedorov(7), Hátylas Azevedo(7), Alessandra Mascarello(7)