Carrow I. Wells

University of North Carolina at Chapel Hill — United States

Materials Science · Physical Sciences

26h-index2.8kcitations189works0.72yr avg
OpenAlex↗ORCID↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Crystallization and Solubility Studies(42), X-ray Diffraction in Crystallography(42), Computational Drug Discovery Methods(28), Cancer-related Molecular Pathways(25), Protein Kinase Regulation and GTPase Signaling(21)

Publications188 total

Identification and Optimization of 4‐Anilinoquinolines as Inhibitors of Cyclin G Associated Kinase
UNC Libraries·2025Open Access
Design of a Cyclin G Associated Kinase (GAK)/Epidermal Growth Factor Receptor (EGFR) Inhibitor Set to Interrogate the Relationship of EGFR and GAK in Chordoma
UNC Libraries·2025Open Access
Identification of 4‐Anilinoquin(az)oline as a Cell‐Active Protein Kinase Novel 3 (PKN3) Inhibitor Chemotype
UNC Libraries·2025Open Access
Targeting STK17B kinase activates ferroptosis and suppresses drug resistance in multiple myeloma
Blood·2025· 1 citedOpen Access
Development of a potent and selective chemical probe for the pleiotropic kinase CK2
UNC Libraries·2025Open Access
Discovery and optimization of narrow spectrum inhibitors of Tousled like kinase 2 (TLK2) using quantitative structure activity relationships
UNC Libraries·2025Open Access
Structural insights into human brachyury DNA recognition and discovery of progressible binders for cancer therapy
Nature Communications·2025· 5 citedOpen Access
Investigation of the Host Kinome Response to Coronavirus Infection Reveals PI3K/mTOR Inhibitors as Betacoronavirus Antivirals
UNC Libraries·2024Open Access
Generative and reinforcement learning approaches for the automated de novo design of bioactive compounds
UNC Libraries·2024Open Access
Application of Integrated Drug Screening/Kinome Analysis to Identify Inhibitors of Gemcitabine-Resistant Pancreatic Cancer Cell Growth
UNC Libraries·2024Open Access
Discovery of Two Highly Selective Structurally Orthogonal Chemical Probes for Activin Receptor-like Kinases 1 and 2
Journal of Medicinal Chemistry·2024· 2 citedOpen Access
Discovery and Characterization of a Chemical Probe for Cyclin-Dependent Kinase-Like 2
ACS Medicinal Chemistry Letters·2024Open Access
Structures of the human transcription factor brachyury offer insights into DNA recognition, and identify small molecule binders for the development of degraders for cancer therapy
2024Open Access
Discovery and Characterization of a Chemical Probe for Cyclin-Dependent Kinase-Like 2
2024Open Access
Discovery and optimization of narrow spectrum inhibitors of Tousled like kinase 2 (TLK2) using quantitative structure activity relationships
European Journal of Medicinal Chemistry·2024· 3 citedOpen Access
Discovery and Optimization of Narrow Spectrum Inhibitors of Tousled Like Kinase 2 (TLK2) Using Quantitative Structure Activity Relationships
2023· 1 citedOpen Access
Investigation of the Host Kinome Response to Coronavirus Infection Reveals PI3K/mTOR Inhibitors as Betacoronavirus Antivirals
Journal of Proteome Research·2023· 14 cited
Discovery and characterization of a specific inhibitor of serine-threonine kinase cyclin-dependent kinase-like 5 (CDKL5) demonstrates role in hippocampal CA1 physiology
eLife·2023· 14 citedOpen Access
Author response: Discovery and characterization of a specific inhibitor of serine-threonine kinase cyclin-dependent kinase-like 5 (CDKL5) demonstrates role in hippocampal CA1 physiology
2023· 1 citedOpen Access
Discovery and characterization of a specific inhibitor of serine-threonine kinase cyclin dependent kinase-like 5 (CDKL5) demonstrates role in hippocampal CA1 physiology
2023Open Access
page 1 of 10Next →

Frequent Co-authors

David H. Drewry(35), William J. Zuercher(26), Timothy M. Willson(25), Alison D. Axtman(16), Jonathan M. Elkins(12), Christopher R. M. Asquith(11), Stefan Knapp(9), Susanne Müller(9), Rafael M. Couñago(9), Stephen J. Capuzzi(7), O. Gileadi(7), Julie E. Pickett(7), James M. Bennett(7), Paulo H. Godoi(6), Tuomo Laitinen(6), Michael P. East(5), Benjamin J. Eduful(5), Hassan Al‐Ali(4), Peter Ettmayer(4), Mathias Frederiksen(4)