Nancy L. Haigwood

Oregon National Primate Research Center — United States

Immunology and Microbiology · Life Sciences

51h-index8.7kcitations175works5.52yr avg
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Research Topics

HIV Research and Treatment(136), Immune Cell Function and Interaction(43), HIV/AIDS drug development and treatment(33), Herpesvirus Infections and Treatments(25), Monoclonal and Polyclonal Antibodies Research(25)

Publications175 total

Monoclonal Antibodies for Pediatric Viral Disease Prevention and Treatment
PEDIATRICS·2025· 1 cited
8.1 – 00022 Short-term Combination Immunotherapy with bNAbs and CCR5 Blockade Mediates ART-Free Viral Control in Infant Rhesus Macaques
Journal of Virus Eradication·2024Open Access
Immune perturbation following SHIV infection is greater in newborn macaques than in infants
JCI Insight·2024· 1 citedOpen Access
Engineered deletions of HIV replicate conditionally to reduce disease in nonhuman primates
Science·2024· 20 citedOpen Access
Aerosol delivery of SARS-CoV-2 human monoclonal antibodies in macaques limits viral replication and lung pathology
Nature Communications·2023· 17 citedOpen Access
Evidence for the Role of a Second Fc-Binding Receptor in Placental IgG Transfer in Nonhuman Primates
mBio·2023· 14 citedOpen Access
Targeting tonsillar B cells with IL-9 and IL-33 enhances the rhesus macaque humoral response to DNA/protein-based HIV envelope vaccine
The Journal of Immunology·2022
Differential V2-directed antibody responses in non-human primates infected with SHIVs or immunized with diverse HIV vaccines
Nature Communications·2022· 11 citedOpen Access
Phagocytosis by an HIV antibody is associated with reduced viremia irrespective of enhanced complement lysis
Nature Communications·2022· 31 citedOpen Access
CD4+ T Cells Are Dispensable for Induction of Broad Heterologous HIV Neutralizing Antibodies in Rhesus Macaques
Frontiers in Immunology·2021· 1 citedOpen Access
Differential V2-directed Antibody Responses in Non-human Primates Infected with SHIVs or Immunized with Diverse HIV Vaccines
2021Open Access
A large repertoire of B cell lineages targeting one cluster of epitopes in a vaccinated rhesus macaque
Vaccine·2021· 3 citedOpen Access
Improved delivery of broadly neutralizing antibodies by nanocapsules suppresses SHIV infection in the CNS of infant rhesus macaques
PLoS Pathogens·2021· 12 citedOpen Access
Protection of Newborn Macaques by Plant-Derived HIV Broadly Neutralizing Antibodies: a Model for Passive Immunotherapy during Breastfeeding
Journal of Virology·2021· 9 citedOpen Access
Antibody-based CCR5 blockade protects Macaques from mucosal SHIV transmission
Nature Communications·2021· 19 citedOpen Access
Advancing HIV Broadly Neutralizing Antibodies: From Discovery to the Clinic
Frontiers in Public Health·2021· 47 citedOpen Access
Effects of persistent modulation of intestinal microbiota on SIV/HIV vaccination in rhesus macaques
npj Vaccines·2021· 12 citedOpen Access
Modified Adenovirus Prime-Protein Boost Clade C HIV Vaccine Strategy Results in Reduced Viral DNA in Blood and Tissues Following Tier 2 SHIV Challenge
Frontiers in Immunology·2021· 5 citedOpen Access
Virus Control in Vaccinated Rhesus Macaques Is Associated with Neutralizing and Capturing Antibodies against the SHIV Challenge Virus but Not with V1V2 Vaccine–Induced Anti-V2 Antibodies Alone
The Journal of Immunology·2021· 9 citedOpen Access
Polyfunctional Tier 2–Neutralizing Antibodies Cloned following HIV-1 Env Macaque Immunization Mirror Native Antibodies in a Human Donor
The Journal of Immunology·2021· 6 citedOpen Access
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Frequent Co-authors

David C. Montefiori(7), William F. Sutton(7), John R. Mascola(5), Philip R. Johnson(5), Ann J. Hessell(5), Nicole A. Doria‐Rose(5), Marta L. Marthas(5), Tatsuhiko Igarashi(4), Dennis R. Burton(4), Andrew J. Watson(4), Shiu-Lok Hu(4), Vanessa M. Hirsch(4), Barbra A. Richardson(4), Riri Shibata(3), Alicia Buckler‐White(3), Malcolm A. Martin(3), Carl J. Scandella(3), Jane Ranchalis(3), Amarendra Pegu(3), Madhumita Mahalanabis(3)