Michal Šála

Czech Academy of Sciences, Institute of Organic Chemistry and Biochemistry — Czech Republic

Biochemistry, Genetics and Molecular Biology · Life Sciences

21h-index1.4kcitations117works4.32yr avg
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Research Topics

Chromatin Remodeling and Cancer(34), Protein Degradation and Inhibitors(17), Retinoids in leukemia and cellular processes(16), Biochemical and Molecular Research(16), DNA and Nucleic Acid Chemistry(14)

Publications117 total

C7-Sulfonamide functionalization of 7-deazaadenosines: sangivamycin analogues with Haspin inhibitory activity
Chemical Communications·2025Open Access
Author response for "C7-Sulfonamide Functionalization of 7-Deazaadenosines: Sangivamycin Analogues with Haspin Inhibitory Activity"
2025
Fluorinated cGAMP analogs, which act as STING agonists and are not cleavable by poxins: Structural basis of their function
Structure·2024· 6 citedOpen Access
Discovery of highly potent SARS-CoV-2 nsp14 methyltransferase inhibitors based on adenosine 5′-carboxamides
RSC Medicinal Chemistry·2024· 11 citedOpen Access
Design, synthesis and evaluation of novel thieno[2,3d]pyrimidine derivatives as potent and specific RIPK2 inhibitors
Bioorganic & Medicinal Chemistry Letters·2023· 1 citedOpen Access
Reactivation of the G1 enhancer landscape underlies core circuitry addiction to SWI/SNF
Nucleic Acids Research·2023· 14 citedOpen Access
Fluorinated cGAMP analogs, which act as STING agonists and are not cleavable by poxins: structural basis of their function
2023· 2 citedOpen Access
Exploring positions 6 and 7 of a quinazoline-based scaffold leads to changes in selectivity and potency towards RIPK2/3 kinases
European Journal of Medicinal Chemistry·2023· 5 citedOpen Access
Inhibition of FLT3-ITD Kinase in Acute Myeloid Leukemia by New Imidazo[1,2-<i>b</i>]pyridazine Derivatives Identified by Scaffold Hopping
Journal of Medicinal Chemistry·2023· 10 citedOpen Access
Rational Design of Highly Potent SARS-CoV-2 nsp14 Methyltransferase Inhibitors
ACS Omega·2023· 28 citedOpen Access
Hydrogen-Bonding Interactions of 8-Substituted Purine Derivatives
ACS Omega·2023· 5 citedOpen Access
Supplementary Data from SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia
2023Open Access
Supplementary Dataset 3 from SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia
2023Open Access
Supplementary Dataset 2 from SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia
2023Open Access
Supplementary Dataset 1 from SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia
2023Open Access
Supplementary Data from SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia
2023Open Access
Supplementary Dataset 3 from SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia
2023Open Access
Supplementary Dataset 4 from SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia
2023Open Access
Supplementary Dataset 1 from SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia
2023Open Access
Supplementary Dataset 2 from SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia
2023Open Access
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Frequent Co-authors

Radim Nencka(37), Milan Dejmek(25), Martin Dračínský(25), Hubert Hřebabecký(23), Evžen Bouřa(14), Eliška Procházková(13), Helena Mertlíková‐Kaiserová(11), Johan Neyts(11), Pieter Leyssen(8), Dominika Chalupská(7), Pavla Plačková(7), Tomáš Otava(5), Martin Klíma(5), Jan Weber(5), Antonı́n Holý(5), Masoud Vedadi(4), Daniel Růžek(4), Armando M. De Palma(4), Karel Chalupský(4), Jindřich Fanfrlík(3)