Vikram V. Shende

Scripps Institution of Oceanography — United States

Medicine · Health Sciences

9h-index587citations35works16.22yr avg
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Research Topics

Microbial Natural Products and Biosynthesis(17), Microbial Metabolism and Applications(8), Enzyme Structure and Function(6), Alkaloids: synthesis and pharmacology(6), Marine Sponges and Natural Products(4)

Publications35 total

P450 Electron transfer: Towards in vitro NAD(P)H-independent biocatalysis
Journal of Inorganic Biochemistry·2025
Identification of an Induced Orthosteric Pocket in IL-23: A New Avenue for Non-biological Therapeutic Targeting
ACS Chemical Biology·2025Open Access
Isolation of Verrucosins A–E from a Marine <i>Verrucosispora</i> sp. Reveals a Unifying Biosynthetic Hypothesis for Linear and Macrocyclic Polyketides
Journal of Natural Products·2025Open Access
Engineering a Biosynthetic Pathway to Produce (+)-Brevianamides A and B
ACS Catalysis·2025· 4 citedOpen Access
Engineering a Biosynthetic Pathway for the Production of (+)-Brevianamides A and B in <i>Escherichia coli</i>
2024Open Access
Correction to “Structure and Biosynthesis of Hectoramide B, a Linear Depsipeptide from Marine Cyanobacterium Moorena producens JHB Discovered via Coculture with <i>Candida albicans</i>”
ACS Chemical Biology·2024· 1 citedOpen Access
Giant polyketide synthase enzymes in the biosynthesis of giant marine polyether toxins
Science·2024· 27 citedOpen Access
Structure and Biosynthesis of Hectoramide B, a Linear Depsipeptide from Marine Cyanobacterium <i>Moorena producens</i> JHB Discovered via Coculture with <i>Candida albicans</i>
ACS Chemical Biology·2024· 6 citedOpen Access
Giant polyketide synthase enzymes biosynthesize a giant marine polyether biotoxin
2024· 5 citedOpen Access
The shikimate pathway: gateway to metabolic diversity
Natural Product Reports·2024· 119 citedOpen Access
Structure and Biosynthesis of Hectoramide B, a Linear Depsipeptide from the Marine Cyanobacterium <i>Moorena producens</i> JHB Discovered via Co-culture with <i>Candida albicans</i>
2023Open Access
Molecular Dynamics Simulations Guide Chimeragenesis and Engineered Control of Chemoselectivity in Diketopiperazine Dimerases
Angewandte Chemie International Edition·2023· 27 citedOpen Access
Molecular Dynamics Simulations Guide Chimeragenesis and Engineered Control of Chemoselectivity in Diketopiperazine Dimerases
Angewandte Chemie·2023· 4 citedOpen Access
Data Science-Driven Analysis of Substrate-Permissive Diketopiperazine Reverse Prenyltransferase NotF: Applications in Protein Engineering and Cascade Biocatalytic Synthesis of (−)-Eurotiumin A
Journal of the American Chemical Society·2022· 37 citedOpen Access
Enzymatic assembly of the salinosporamide γ-lactam-β-lactone anticancer warhead
Nature Chemical Biology·2022· 35 citedOpen Access
Structural and Data Science-Driven Analysis to Assess Substrate Specificity of Diketopiperazine Reverse Prenyltransferase NotF: Cascade Biocatalytic Synthesis of (–)-Eurotiumin A
2021Open Access
Structural and Data Science-Driven Analysis to Assess Substrate Specificity of Diketopiperazine Reverse Prenyltransferase NotF: Cascade Biocatalytic Synthesis of (–)-Eurotiumin A
2021Open Access
Structure and Function of NzeB, a Versatile C–C and C–N Bond-Forming Diketopiperazine Dimerase
Journal of the American Chemical Society·2020· 78 citedOpen Access
CCDC 1973958: Experimental Crystal Structure Determination
The Cambridge Structural Database·2020Open Access
CCDC 1973959: Experimental Crystal Structure Determination
The Cambridge Structural Database·2020Open Access
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Frequent Co-authors

David H. Sherman(21), Sean A. Newmister(19), Amy E. Fraley(10), Sachiko Tsukamoto(10), Robert S. Paton(10), K. N. Houk(10), Robert M. Williams(9), Jacob N. Sanders(9), Atsushi Minami(7), Maria L. Adrover‐Castellano(7), Nolan Carney(7), Janet L. Smith(7), Yogan Khatri(7), Shuai Mu(6), Hideaki Oikawa(6), Shengying Li(6), Qingyun Dan(6), Fengan Yu(6), Hikaru Kato(5), Petra Lindovská(5)