L S Zalman

Medicine · Health Sciences

24h-index2.9kcitations39works125.02yr avg
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Research Topics

Monoclonal and Polyclonal Antibodies Research(13), Viral Infections and Immunology Research(11), Complement system in diseases(10), Respiratory viral infections research(9), Erythrocyte Function and Pathophysiology(5)

Publications39 total

The Immune Epitope Database (IEDB): 2024 update
Nucleic Acids Research·2024· 125 citedOpen Access
A behind‐the‐scenes tour of the IEDB curation process: an optimized process empirically integrating automation and human curation efforts
Immunology·2020· 8 citedOpen Access
In Vitro Antiviral Activity and Single-Dose Pharmacokinetics in Humans of a Novel, Orally Bioavailable Inhibitor of Human Rhinovirus 3C Protease
Antimicrobial Agents and Chemotherapy·2005· 133 citedOpen Access
Conservation of Amino Acids in Human Rhinovirus 3C Protease Correlates with Broad-Spectrum Antiviral Activity of Rupintrivir, a Novel Human Rhinovirus 3C Protease Inhibitor
Antimicrobial Agents and Chemotherapy·2005· 156 citedOpen Access
Phase II, Randomized, Double-Blind, Placebo-Controlled Studies of Ruprintrivir Nasal Spray 2-Percent Suspension for Prevention and Treatment of Experimentally Induced Rhinovirus Colds in Healthy Volunteers
Antimicrobial Agents and Chemotherapy·2003· 230 citedOpen Access
An optical thin film assay incorporating rhinovirus protease inhibitors as detector reagents
Antiviral Research·2003
Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 8. Pharmacological Optimization of Orally Bioavailable 2-Pyridone-Containing Peptidomimetics
Journal of Medicinal Chemistry·2003· 113 cited
Structure-Based Design of a Parallel Synthetic Array Directed Toward the Discovery of Irreversible Inhibitors of Human Rhinovirus 3C Protease
Journal of Medicinal Chemistry·2002· 37 citedOpen Access
Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 6. Structure−Activity Studies of Orally Bioavailable, 2-Pyridone-Containing Peptidomimetics
Journal of Medicinal Chemistry·2002· 140 citedOpen Access
Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. Part 7: Structure–Activity Studies of Bicyclic 2-Pyridone-Containing Peptidomimetics
Bioorganic & Medicinal Chemistry Letters·2002· 78 cited
Rapid multiserotype detection of human rhinoviruses on optically coated silicon surfaces
Journal of Clinical Virology·2001· 20 citedOpen Access
Inhibition of Human Rhinovirus-Induced Cytokine Production by AG7088, a Human Rhinovirus 3C Protease Inhibitor
Antimicrobial Agents and Chemotherapy·2000· 58 cited
Structure-based design of ketone-containing, tripeptidyl human rhinovirus 3C protease inhibitors
Bioorganic & Medicinal Chemistry Letters·2000· 43 cited
In Vitro Antiviral Activity of AG7088, a Potent Inhibitor of Human Rhinovirus 3C Protease
Antimicrobial Agents and Chemotherapy·1999· 223 citedOpen Access
Structure-assisted design of mechanism-based irreversible inhibitors of human rhinovirus 3C protease with potent antiviral activity against multiple rhinovirus serotypes
Proceedings of the National Academy of Sciences·1999· 316 cited
A novel anti-rhinoviral compound directed at 3C protease can diminish IL-6 and IL-8 production in a transformed bronchial epithelial cell line
Antiviral Research·1997· 1 cited
Evaluation of the antiviral activity and cytotoxicity of peptidic inhibitors of human rhinovirus 3C protease, a novel target for antiviral intervention
Antiviral Research·1997· 7 cited
Comparison of human cytomegalovirus (HCMV) protease sequences among laboratory strains and seven clinical isolates
Antiviral Research·1997· 4 cited
Homologous restriction factor: Effect on complement C8 and C9 uptake and lysis
Molecular Immunology·1994· 3 cited
Homologous Restriction Factor
Current topics in microbiology and immunology·1992· 14 cited
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Frequent Co-authors

Amy K. Patick(15), Hans J. Müller‐Eberhard(13), Shella A. Fuhrman(10), James W. Meador(10), M. A. Brothers(10), Stephen T. Worland(10), Peter S. Dragovich(9), David A. Matthews(8), Thomas J. Prins(8), Ru Zhou(7), Edward L. Brown(7), Susan L. Binford(7), Rose Ann Ferre(6), Fausto C. Maldonado(5), Hiroshi Nikaido(4), D E Martin(4), S. E. Webber(3), Thomas F. Hendrickson(3), L M Wood(3), Fausto Maldonado(3)