Nancy M. Hannett

Whitehead Institute for Biomedical Research — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

31h-index24.9kcitations58works8.32yr avg
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Research Topics

Genomics and Chromatin Dynamics(25), RNA Research and Splicing(22), RNA and protein synthesis mechanisms(16), Advanced Breast Cancer Therapies(10), RNA modifications and cancer(7)

Publications58 total

APE1 condensation in nucleoli of non-cancer cells depends on rRNA transcription and forming G-quadruplex RNA structures
Nucleic Acids Research·2025· 4 citedOpen Access
Proteolethargy is a pathogenic mechanism in chronic disease
Cell·2024· 21 citedOpen Access
Nucleolar accumulation of APE1 through condensates is mediated by rRNA forming G-quadruplex structures
2024Open Access
Author Correction: Distinct chemical environments in biomolecular condensates
Nature Chemical Biology·2023· 3 citedOpen Access
Distinct chemical environments in biomolecular condensates
Nature Chemical Biology·2023· 94 citedOpen Access
Transcription factors interact with RNA to regulate genes
Molecular Cell·2023· 234 citedOpen Access
The dynamic clustering of insulin receptor underlies its signaling and is disrupted in insulin resistance
Nature Communications·2022· 45 citedOpen Access
Transcription factors interact with RNA to regulate genes
2022· 23 citedOpen Access
Genetic variation associated with condensate dysregulation in disease
Developmental Cell·2022· 97 citedOpen Access
Abstract GS3-10: Partitioning of cancer therapeutics in nuclear condensates
Cancer Research·2021
RNA-Mediated Feedback Control of Transcriptional Condensates
Cell·2020· 590 citedOpen Access
MeCP2 links heterochromatin condensates and neurodevelopmental disease
Nature·2020· 196 citedOpen Access
Partitioning of cancer therapeutics in nuclear condensates
Science·2020· 506 citedOpen Access
Mediator Condensates Localize Signaling Factors to Key Cell Identity Genes
Molecular Cell·2019· 292 citedOpen Access
Enhancer Features that Drive Formation of Transcriptional Condensates
Molecular Cell·2019· 413 citedOpen Access
Pol II phosphorylation regulates a switch between transcriptional and splicing condensates
Nature·2019· 689 citedOpen Access
Enhancer features that drive formation of transcriptional condensates
2018· 31 citedOpen Access
Transcription Factors Activate Genes through the Phase-Separation Capacity of Their Activation Domains
DSpace@MIT (Massachusetts Institute of Technology)·2018Open Access
Transcription Factors Activate Genes through the Phase-Separation Capacity of Their Activation Domains
Cell·2018· 1.8k citedOpen Access
Coactivator condensation at super-enhancers links phase separation and gene control
DSpace@MIT (Massachusetts Institute of Technology)·2018Open Access
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Frequent Co-authors

Richard A. Young(43), Tong Ihn Lee(19), Brian J. Abraham(18), Alicia V. Zamudio(11), Nathanael S. Gray(11), Nicholas Kwiatkowski(11), Jonathan E. Henninger(11), Alessandra Dall’Agnese(10), Tinghu Zhang(10), Ann Boija(9), Scott B. Ficarro(9), Jarrod A. Marto(9), Benjamin R. Sabari(8), Eliot L. Coffey(8), Krishna Shrinivas(8), Phillip A. Sharp(8), Julia Zeitlinger(7), Isaac A. Klein(7), Charles H. Li(7), Yang Guo(7)