Robert Mintzer

Medicine · Health Sciences

11h-index924citations12works0.02yr avg
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Research Topics

Cancer-related Molecular Pathways(3), Sphingolipid Metabolism and Signaling(3), Peptidase Inhibition and Analysis(3), Protein Kinase Regulation and GTPase Signaling(2), Lipid Membrane Structure and Behavior(2)

Publications12 total

A Putative Bacterial ABC Transporter Circumvents the Essentiality of Signal Peptidase
mBio·2016· 19 citedOpen Access
Synthesis and evaluation of a series of 4-azaindole-containing p21-activated kinase-1 inhibitors
Bioorganic & Medicinal Chemistry Letters·2016· 18 citedOpen Access
Structure-Guided Design of Group I Selective p21-Activated Kinase Inhibitors
Journal of Medicinal Chemistry·2015· 37 citedOpen Access
Back Pocket Flexibility Provides Group II p21-Activated Kinase (PAK) Selectivity for Type I 1/2 Kinase Inhibitors
Journal of Medicinal Chemistry·2014· 63 citedOpen Access
CCDC 1013531: Experimental Crystal Structure Determination
The Cambridge Structural Database·2014Open Access
Histone Deacetylase (HDAC) Inhibitor Kinetic Rate Constants Correlate with Cellular Histone Acetylation but Not Transcription and Cell Viability
Journal of Biological Chemistry·2013· 401 citedOpen Access
A Whole Cell Assay to Measure Caspase-6 Activity by Detecting Cleavage of Lamin A/C
PLoS ONE·2012· 23 citedOpen Access
A Novel High-Throughput Screening Format to Identify Inhibitors of Secreted Acid Sphingomyelinase
SLAS DISCOVERY·2005· 14 citedOpen Access
A model of the acid sphingomyelinase phosphoesterase domain based on its remote structural homolog purple acid phosphatase
Protein Science·2004· 23 citedOpen Access
Differential Effects of IFN-β1b on the Proliferation of Human Vascular Smooth Muscle and Endothelial Cells
Journal of Interferon & Cytokine Research·1998· 17 cited
Beyond drug therapy: Nonpharmacologic care of the patient with advanced heart failure
American Heart Journal·1998· 37 cited
Human Vascular Endothelial Cells Are a Rich and Regulatable Source of Secretory Sphingomyelinase
Journal of Biological Chemistry·1998· 272 citedOpen Access

Frequent Co-authors

Christopher E. Heise(7), Lionel Rougé(4), Joachim Rudolph(4), Weiru Wang(4), Klaus P. Hoeflich(4), Christine Tam(3), Sreemathy Ramaswamy(3), Zora Modrušan(2), Ira Tabas(2), Steven T. Staben(2), Jianwen A. Feng(2), Karen S. Lyle(2), Marcia Belvin(2), Jason Boggs(2), Jason D. Burch(2), Haifeng Cui(2), Antonio G. DiPasquale(2), Lori S. Friedman(2), Hartmut Koeppen(2), Adrian Kotey(2)