Ivan Zlatev

Alnylam Pharmaceuticals (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

26h-index3.0kcitations84works2.82yr avg
OpenAlex↗ORCID↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

RNA Interference and Gene Delivery(34), Advanced biosensing and bioanalysis techniques(23), DNA and Nucleic Acid Chemistry(17), Renin-Angiotensin System Studies(11), Crystallization and Solubility Studies(11)

Publications84 total

Abstract TAC105: High Salt Intake Enhances the REVERSIR-Induced Recovery of Blood Pressure after Angiotensinogen siRNA Treatment
Hypertension·2025
PERSISTENT BENEFICIAL EFFECTS OF ANGIOTENSINOGEN SMALL INTERFERING RNA (SIRNA) AND VALSARTAN IN SPONTANEOUSLY HYPERTENSIVE RATS AFTER DRUG REMOVAL
Journal of Hypertension·2025
In vivo expansion of gene-targeted hepatocytes through transient inhibition of an essential gene
Science Translational Medicine·2025· 5 cited
Kidney Arteriolar Responses to Liver‐Targeted Small Interference RNA Targeting Angiotensinogen in Diabetic Rats: Comparison With Other Renin‐Angiotensin System Blockers
Journal of the American Heart Association·2025· 4 citedOpen Access
DEVELOPMENT OF A МULTI-PURPOSE MONITORING AND CONTROL SYSTEM BASED ON ZIGBEE WIRELESS SENSOR NETWORK
INTERNATIONAL SCIENTIFIC CONFERENCE - UNITECH·2025
REAL-TIME NETWORK TRAFFIC ANALYSIS AND OPTIMIZATION
INTERNATIONAL SCIENTIFIC CONFERENCE - UNITECH·2025
High resistance barrier and prophylactic protection in preclinical models of SARS-CoV-2 with two siRNA combination
Nucleic Acids Research·2024· 5 citedOpen Access
An Investigational RNAi Therapeutic for Tau Lowering
Alzheimer s & Dementia·2024· 1 citedOpen Access
Single-Stranded Hairpin Loop RNAs (loopmeRNAs) Potently Induce Gene Silencing through the RNA Interference Pathway
Journal of the American Chemical Society·2024· 1 cited
Abstract 18: Persistent beneficial effects of angiotensinogen small interfering RNA (siRNA) and valsartan in spontaneously hypertensive rats after drug removal
Hypertension·2024
Abstract P104: Kidney arteriolar responses to liver-targeted small interference RNA (siRNA) targeting angiotensinogen in diabetic rats: comparison with other renin-angiotensin system blockers
Hypertension·2024· 1 cited
O52 KIDNEY ARTERIOLAR RESPONSES TO LIVER-TARGETED SMALL INTERFERENCE RNA (SIRNA) TARGETING ANGIOTENSINOGEN IN DIABETIC RATS: COMPARISON WITH OTHER RENIN-ANGIOTENSIN SYSTEM BLOCKERS
Journal of Hypertension·2024
Evaluating the oral delivery of GalNAc-conjugated siRNAs in rodents and non-human primates
Nucleic Acids Research·2024· 9 citedOpen Access
Counteracting Angiotensinogen Small-Interfering RNA-Mediated Antihypertensive Effects With REVERSIR
Hypertension·2024· 16 citedOpen Access
COUNTERACTING ANGIOTENSINOGEN SMALL INTERFERING RNA-MEDIATED ANTIHYPERTENSIVE EFFECTS WITH REVERSIR
Journal of Hypertension·2024
RNAi knockdown of microtubule‐associated protein Tau prevents axonal damage and clears pre‐existing Tau aggregates in P301S transgenic tauopathy model mice
Alzheimer s & Dementia·2023· 2 citedOpen Access
An Investigational RNAi Therapeutic for Tau Lowering
Alzheimer s & Dementia·2023· 1 citedOpen Access
Targeting Angiotensinogen With <i>N</i> -Acetylgalactosamine–Conjugated Small Interfering RNA to Reduce Blood Pressure
Arteriosclerosis Thrombosis and Vascular Biology·2023· 16 citedOpen Access
Shorter Is Better: The α-(<scp>l</scp>)-Threofuranosyl Nucleic Acid Modification Improves Stability, Potency, Safety, and Ago2 Binding and Mitigates Off-Target Effects of Small Interfering RNAs
Journal of the American Chemical Society·2023· 37 citedOpen Access
<i>In vivo</i> expansion of gene-targeted hepatocytes through transient inhibition of an essential gene
2023· 2 citedOpen Access
page 1 of 5Next →

Frequent Co-authors

Muthiah Manoharan(29), Martin A. Maier(20), Mark K. Schlegel(15), Vasant Jadhav(15), Klaus Charissé(15), Shigeo Matsuda(13), Kallanthottathil G. Rajeev(13), Martin Egli(13), Adam Castoreno(12), Christopher R. Brown(11), Anna Bisbe(10), Kelly Wassarman(9), Christopher S. Theile(8), Jayaprakash K. Nair(8), Maja M. Janas(8), Donald J. Foster(8), Dale C. Guenther(8), Jean‐Jacques Vasseur(8), F. Morvan(8), Yongfeng Jiang(7)