Christine Kinnon

Biochemistry, Genetics and Molecular Biology · Life Sciences

44h-index10.7kcitations196works0.02yr avg
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Research Topics

Virus-based gene therapy research(51), Immunodeficiency and Autoimmune Disorders(51), Health, Medicine and Society(34), Hermeneutics and Narrative Identity(34), Aging, Elder Care, and Social Issues(34)

Publications196 total

Prospects for gene therapy of X-linked immunodeficiency diseases
Garland Science eBooks·2024
Gene therapy for adenosine deaminase deficiency
Gene Therapy·2020
Molecular Evidence of Genome Editing in a Mouse Model of Immunodeficiency
Scientific Reports·2018· 8 citedOpen Access
Enhancement of mouse hematopoietic stem/progenitor cell function via transient gene delivery using integration-deficient lentiviral vectors
Experimental Hematology·2017· 5 citedOpen Access
Molecular Evidence of Ex Vivo Gene Editing in a Mouse Model of Immunodeficiency
UCL Discovery (University College London)·2017
X-SCID paper 2011
2014
Rescue of T-cell deficiency in PRKDC SCID mice by transplantation of gene-edited haematopoietic stem cells
UCL Discovery (University College London)·2013
Developing lentiviral vectors for gene thrapy of type I Gaucher disease
UCL Discovery (University College London)·2013
Rescue of mouse Prkdc scid deficiency by transplantation of gene-repaired haematopoietic stem cells
2013
Manipulation of haematopoietic stem cell biology using transient gene expression from integration-deficient lentiviral vectors
UCL Discovery (University College London)·2013
Animal Models of Human Primary Immunodeficiency Diseases
Encyclopedia of Life Sciences·2012· 1 cited
Transient manipulation of haematopoietic stem cells with integrative deficient lentiviral vectors for improved cell expansion, survival and engraftment
UCL Discovery (University College London)·2012
Specificity of a zinc-finger nuclease targeting mouse Prkdc: preparation of samples for analysis of off-target cutting
2012
Developing lentiviral vectors for gene therapy of Type I Gaucher Disease
UCL Discovery (University College London)·2012
Pillars Article: The Gene Involved in X-linked Agammaglobulinaemia Is a Member of the Src Family of Protein-Tyrosine Kinases. <i>Nature</i>. 1993. 361: 226–233
The Journal of Immunology·2012· 4 cited
Persistence of a polyclonal T-cell repertoire in patients with SCID-X1 following gene therapy
UCL Discovery (University College London)·2011
Lentiviral vectors for gene therapy of Type I Gaucher Disease
UCL Discovery (University College London)·2011
Targeting models of severe combined immunodeficiency for correction by zinc finger nucleases
UCL Discovery (University College London)·2011
Development of a clinical trial of gene therapy for X-CGD using the pCCLCHIMGp91WPRE4 lentiviral vector
UCL Discovery (University College London)·2011
Hematopoietic Stem Cell Gene Therapy for Adenosine Deaminase–Deficient Severe Combined Immunodeficiency Leads to Long-Term Immunological Recovery and Metabolic Correction
Science Translational Medicine·2011· 281 citedOpen Access
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Frequent Co-authors

Adrian J. Thrasher(33), Kimberly Gilmour(10), H. Bobby Gaspar(9), Steven J. Howe(7), Kathryn L. Parsley(7), Michael P. Blundell(7), Roland J. Levinsky(6), Joanna Sinclair(6), Robin R. Ali(6), Giles O. Cory(6), Gareth E. Jones(5), Stuart Adams(4), Jinhua Bayford(4), Manfred Schmidt(4), Christof von Kalle(4), E. Graham Davies(4), Paul Veys(4), Yolanda Calle(4), Paul M. Brickell(4), Steve Hinshelwood(4)