Jinhua Bayford

Great Ormond Street Hospital — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

6h-index2.1kcitations12works0.02yr avg
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Research Topics

Virus-based gene therapy research(8), CAR-T cell therapy research(8), RNA Interference and Gene Delivery(3), Immune Cell Function and Interaction(2), Health, Medicine and Society(2)

Publications12 total

Long-term safety and efficacy of lentiviral hematopoietic stem/progenitor cell gene therapy for Wiskott–Aldrich syndrome
Nature Medicine·2022· 112 citedOpen Access
Long-term lymphoid progenitors independently sustain naïve T and NK cell production in humans
Nature Communications·2021· 6 citedOpen Access
Bipotent Lymphoid Progenitors Independently Maintain Long-Term Genetically Engineered T and NK Cell Production in Humans
Blood·2020
Lentiviral Gene Therapy with Autologous Hematopoietic Stem and Progenitor Cells (HSPCs) for the Treatment of Severe Combined Immune Deficiency Due to Adenosine Deaminase Deficiency (ADA-SCID): Results in an Expanded Cohort
Blood·2019· 14 cited
X-SCID paper 2011
2014
Persistence of a polyclonal T-cell repertoire in patients with SCID-X1 following gene therapy
UCL Discovery (University College London)·2011
Hematopoietic Stem Cell Gene Therapy for Adenosine Deaminase–Deficient Severe Combined Immunodeficiency Leads to Long-Term Immunological Recovery and Metabolic Correction
Science Translational Medicine·2011· 281 citedOpen Access
Immunodeficiency: Long-term persistence of a polyclonal t cell repertoire after gene therapy for X-linked severe combined immunodeficiency
UCL Discovery (University College London)·2011· 2 cited
Long-Term Persistence of a Polyclonal T Cell Repertoire After Gene Therapy for X-Linked Severe Combined Immunodeficiency
Science Translational Medicine·2011· 232 citedOpen Access
Insertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients
Journal of Clinical Investigation·2008· 1.3k citedOpen Access
Reconstitution of immune function in adenosine deaminase deficient severe combined immunodeficiency following hematopoietic stem cell gene therapy
Blood Cells Molecules and Diseases·2008
Gammaretrovirus-mediated correction of SCID-X1 is associated with skewed vector integration site distribution in vivo
Journal of Clinical Investigation·2007· 203 citedOpen Access

Frequent Co-authors

Adrian J. Thrasher(12), Kimberly Gilmour(8), Stuart Adams(8), H. Bobby Gaspar(8), Christine Kinnon(7), Kathryn L. Parsley(5), Samantha Cooray(5), Steven J. Howe(4), Abdulaziz Al Ghonaium(4), Claire Booth(4), Lucinda Brown(3), Christine Rivat(3), Kerstin Schwarzwaelder(2), Martijn H. Brugman(2), Karin Pike‐Overzet(2), Dick de Ridder(2), Frank J. T. Staal(2), Manfred Schmidt(2), Christof von Kalle(2), Fang Zhang(2)