Christopher B. Marotta

California Institute of Technology — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

6h-index92citations16works1.02yr avg
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Research Topics

Nicotinic Acetylcholine Receptors Study(10), Receptor Mechanisms and Signaling(9), Ion channel regulation and function(3), Advanced Biosensing Techniques and Applications(3), Advanced Sensor and Energy Harvesting Materials(2)

Publications16 total

BPS2026 - Computational design of protein-based biosensors toward wearable measuring of nicotine concentration and dynamics
Biophysical Journal·2026
Hydrogel Encapsulation of a Designed Fluorescent Protein Biosensor for Continuous Measurements of Sub-100 nM Nicotine
ACS Applied Bio Materials·2025
Continuous Nicotine Monitors for Personal Nicotine Pharmacokinetics: A Receptor-Aware Research Agenda
Nicotine & Tobacco Research·2025· 1 cited
Hydrogel encapsulation of a designed fluorescent protein biosensor for continuous measurements of sub-100 nanomolar nicotine
2024· 1 citedOpen Access
Method for Quantitative Analysis of Vitreoretinal Adhesion in Ex Vivo Model
Translational Vision Science & Technology·2024Open Access
Interactive computational and experimental approaches improve the sensitivity of periplasmic binding protein-based nicotine biosensors for measurements in biofluids
Protein Engineering Design and Selection·2024· 4 citedOpen Access
β2 nAChR Activation on VTA DA Neurons Is Sufficient for Nicotine Reinforcement in Rats
eNeuro·2023· 9 citedOpen Access
Interactive computational and experimental approaches improve the sensitivity of periplasmic binding protein-based nicotine biosensors for measurements in biofluids
2023· 4 citedOpen Access
Surgery-Guided Removal of Ovarian Cancer Using Up-Converting Nanoparticles
ACS Applied Materials & Interfaces·2020· 7 citedOpen Access
Mutation Linked to Autosomal Dominant Nocturnal Frontal Lobe Epilepsy Reduces Low-Sensitivity α4β2, and Increases α5α4β2, Nicotinic Receptor Surface Expression
PLoS ONE·2016· 23 citedOpen Access
An Unaltered Orthosteric Site and a Network of Long-Range Allosteric Interactions for PNU-120596 in α7 Nicotinic Acetylcholine Receptors
Chemistry & Biology·2015· 8 citedOpen Access
Structure-Function Studies of Nicotinic Acetylcholine Receptors Using Selective Agonists and Positive Allosteric Modulators
2015
Selective Ligand Behaviors Provide New Insights into Agonist Activation of Nicotinic Acetylcholine Receptors
ACS Chemical Biology·2014· 21 citedOpen Access
Identifying Motifs Essential for Selective Activation of Nicotinic Acetylcholine Receptors
Biophysical Journal·2014Open Access
Probing the non-canonical interface for agonist interaction with an α5 containing nicotinic acetylcholine receptor
Neuropharmacology·2013· 14 citedOpen Access
Function of nAChRs Containing Alpha5 Subunits
Biophysical Journal·2012Open Access

Frequent Co-authors

Dennis A. Dougherty(13), Henry A. Lester(12), Aaron L. Nichols(6), Stephen L. Mayo(5), Nicholas J Friesenhahn(3), Daniel A. Wagenaar(3), Anand K. Muthusamy(3), Crystal N. Dilworth(2), Nandan Haloi(2), Shan Huang(2), Eve Fine(2), Erik Lindahl(2), Rebecca J. Howard(2), Sophia R. Dalfonzo(2), Weston A. Nichols(1), Brandon J. Henderson(1), Caroline Yu(1), Chris I. Richards(1), Bruce Cohen(1), Iva Rreza(1)