Darren J. Baker

Mayo Clinic — United States

Medicine · Health Sciences

54h-index25.0kcitations125works37.62yr avg
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Research Topics

Telomeres, Telomerase, and Senescence(45), Microtubule and mitosis dynamics(23), Genetics, Aging, and Longevity in Model Organisms(13), Cancer-related Molecular Pathways(11), Single-cell and spatial transcriptomics(11)

Publications125 total

The Sixth Annual Symposium of the Midwest Aging Consortium
The Journals of Gerontology Series A·2025Open Access
Supplementary Data T1 from Advanced Age in Humans and Mouse Models of Glioblastoma Show Decreased Survival from Extratumoral Influence
2025Open Access
Supplementary Data F1 from Advanced Age in Humans and Mouse Models of Glioblastoma Show Decreased Survival from Extratumoral Influence
2025Open Access
Protein kinase Cι dictates tumor trajectory, cell plasticity, and immune surveillance in lung adenocarcinoma
Cell Reports·2025Open Access
Protocol to test path integration in mice using an L-maze behavioral assay
STAR Protocols·2025Open Access
An Unbiased Cell‐Culture Selection Yields <scp>DNA</scp> Aptamers as Novel Senescent Cell‐Specific Reagents
Aging Cell·2025· 1 citedOpen Access
Advancing biological understanding of cellular senescence with computational multiomics
Nature Genetics·2025· 10 citedOpen Access
Evaluation of [<sup>18</sup>F]F-CNBI and [<sup>18</sup>F]F-CNPI PET Probes in GSK-3β Transgenic Mice
ACS Chemical Neuroscience·2025Open Access
Single-cell and spatial transcriptomics map senescent vascular cells in arterial remodeling during atherosclerosis in mice
Nature Aging·2025· 13 citedOpen Access
<scp>BubR1</scp> Insufficiency Drives Transcriptomic Alterations and Pathology Associated With Cardiac Aging and Heart Failure
Aging Cell·2025· 1 citedOpen Access
p16-expressing microglia and endothelial cells promote tauopathy and neurovascular abnormalities in PS19 mice
Neuron·2025· 9 cited
An unbiased cell-culture selection yields DNA aptamers as novel senescent cell-specific reagents
2025· 1 citedOpen Access
Multi-Modal Spatial Mapping of Cellular Senescence in Human Chronic Wounds from Aged Skin
SSRN Electronic Journal·2025Open Access
IL-23R is a senescence-linked circulating and tissue biomarker of aging
Nature Aging·2024· 22 citedOpen Access
Neuroinflammation in Alzheimer disease
Nature reviews. Immunology·2024· 289 citedOpen Access
Chronic social stress induces p16-mediated senescent cell accumulation in mice
Nature Aging·2024· 16 citedOpen Access
Gene deletion of Pregnancy-associated Plasma Protein-A (PAPP-A) improves pathology and cognition in an Alzheimer's disease mouse model
Experimental Neurology·2024· 2 citedOpen Access
Loss of HD-PTP function results in lipodystrophy, defective cellular signaling and altered lipid homeostasis
Journal of Cell Science·2024· 1 citedOpen Access
Guidelines for minimal information on cellular senescence experimentation in vivo
Cell·2024· 220 citedOpen Access
SenNet recommendations for detecting senescent cells in different tissues
Nature Reviews Molecular Cell Biology·2024· 277 citedOpen Access
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Frequent Co-authors

Jan M. van Deursen(33), Karthik B. Jeganathan(14), Bennett G. Childs(10), Tobias Wijshake(5), James L. Kirkland(5), Ines Sturmlechner(5), Liviu Malureanu(5), Nathan K. LeBrasseur(4), Bart van de Sluis(4), Judith Campisi(4), Laura J. Niedernhofer(4), Tamar Tchkonia(3), Matej Durik(3), Cynthia J. Sieben(3), André Terzic(3), Marissa J. Schafer(3), Virginia Smith Shapiro(3), Cheng Zhang(3), Hu Li(3), Paul D. Robbins(3)