Susruta Majumdar

University of Health Sciences and Pharmacy — United States

Neuroscience · Life Sciences

33h-index4.0kcitations146works3.92yr avg
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Research Topics

Neuropeptides and Animal Physiology(74), Receptor Mechanisms and Signaling(62), Pharmacological Receptor Mechanisms and Effects(41), Alkaloids: synthesis and pharmacology(28), Chemical synthesis and alkaloids(24)

Publications146 total

Divergence in μ and δ opioid receptor pharmacology in neurons and antinociceptive efficacy in neuropathic pain: Insights from MP135 and CYM51010
British Journal of Pharmacology·2026
Non-equilibrium snapshots of ligand efficacy at the μ-opioid receptor
Nature·2025
Differential Effects of Sodium on Agonist-Induced Conformational Transitions and Signaling at μ and κ Opioid Receptors
Biochemistry·2025· 1 cited
Molecular mechanisms of inverse agonism via κ-opioid receptor–G protein complexes
UNC Libraries·2025Open Access
A cryptic pocket in CB1 drives peripheral and functional selectivity
UNC Libraries·2025Open Access
Total synthesis and biological activity of "carbamorphine": O-to-CH2 replacement in the E-ring of the morphine core structure.
UNC Libraries·2025Open Access
Structure-guided design of partial agonists at an opioid receptor
UNC Libraries·2025Open Access
Differential effects of sodium on agonist-induced conformational transitions and signaling at μ and κ opioid receptors
2025Open Access
Total synthesis and biological activity of “carbamorphine”: O-to-CH <sub>2</sub> replacement in the E-ring of the morphine core structure
Proceedings of the National Academy of Sciences·2025· 3 citedOpen Access
Synthesis and Pharmacology of a Morphinan-Derived Dual Mu–Kappa Opioid Receptor Agonist Analgesic
ACS Chemical Neuroscience·2025· 2 cited
Non-Equilibrium Snapshots of Ligand Efficacy at the μ-Opioid Receptor
2025· 4 citedOpen Access
Development of a G-protein Biased Peripherally Restricted Cannabinoid Receptor 1 Agonist
Journal of Pain·2025
Structure-guided design of partial agonists at an opioid receptor
Nature Communications·2025· 7 citedOpen Access
A cryptic pocket in CB1 drives peripheral and functional selectivity
Nature·2025· 26 citedOpen Access
Structural and Functional Characterization of a Novel KOR-Selective Peptide-Drug Conjugate Ligand, DNCP-β-NalA (Abstract ID: 171223)
Journal of Pharmacology and Experimental Therapeutics·2025
Modulation of Kappa Opioid Receptor Functional Selectivity, Efficacy and Subtype Selectivity (Abstract ID: 156788)
Journal of Pharmacology and Experimental Therapeutics·2025
Targeting a Cryptic Pocket in Cannabinoid Receptor 1 Drives Peripheral and Functional Selectivity (Abstract ID: 189377)
Journal of Pharmacology and Experimental Therapeutics·2025
Advances in the structural understanding of opioid allostery
Trends in Pharmacological Sciences·2025· 1 citedOpen Access
Molecular mechanisms of inverse agonism via κ-opioid receptor–G protein complexes
Nature Chemical Biology·2025· 15 citedOpen Access
Oxa-Iboga alkaloids lack cardiac risk and disrupt opioid use in animal models
Nature Communications·2024· 13 citedOpen Access
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Frequent Co-authors

Gavril W. Pasternak(23), Ying‐Xian Pan(17), Valerie Le Rouzic(15), Jin Xu(11), Tao Che(10), Rajendra Uprety(10), András Váradi(9), Steven G. Grinnell(9), Shainnel O. Eans(9), Jay P. McLaughlin(9), Soumen Chakraborty(9), Amanda Hunkele(8), Gina F. Marrone(7), John E. Pintar(7), Balázs R. Varga(7), Bryan L. Roth(6), Joan Subrath(6), Michael Ansonoff(6), Abdelfattah Faouzi(6), Kevin Appourchaux(6)