Fernando W. Sehgelmeble

AstraZeneca (United Kingdom) — United Kingdom

Chemistry · Physical Sciences

8h-index364citations10works0.02yr avg
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Research Topics

Carbohydrate Chemistry and Synthesis(5), Microbial Metabolites in Food Biotechnology(4), Alzheimer's disease research and treatments(2), Computational Drug Discovery Methods(2), Enzyme Production and Characterization(2)

Publications10 total

Core Refinement toward Permeable β-Secretase (BACE-1) Inhibitors with Low hERG Activity
Journal of Medicinal Chemistry·2012· 40 citedOpen Access
N-1-Alkyl-2-oxo-2-aryl amides as novel antagonists of the TRPA1 receptor
Bioorganic & Medicinal Chemistry Letters·2012· 21 citedOpen Access
Synthesis and arylation of unprotected sulfonimidamides
Tetrahedron·2012· 59 cited
Sulfonimidamides as Sulfonamides Bioisosteres: Rational Evaluation through Synthetic, in Vitro, and in Vivo Studies with γ‐Secretase Inhibitors
ChemMedChem·2012· 86 cited
Aminoimidazoles as BACE-1 inhibitors: The challenge to achieve in vivo brain efficacy
Bioorganic & Medicinal Chemistry Letters·2012· 48 citedOpen Access
A stereoselective approach to phosphodiester-linked oligomers of the repeating unit of Escherichia coli K52 capsular polysaccharide containing β-D-fructofuranosyl moieties
Tetrahedron Asymmetry·2004· 16 cited
Chemical Syntheses of Inulin and Levan Structures.
ChemInform·2003Open Access
Chemical Syntheses of Inulin and Levan Structures
The Journal of Organic Chemistry·2002· 31 cited
Stereospecific synthesis of β-D-fructofuranosides : synthesis of sucrose and structures related to plant and bacterial polysaccharides
2002
A Novel β-Directing Fructofuranosyl Donor Concept. Stereospecific Synthesis of Sucrose
Journal of the American Chemical Society·2000· 63 cited

Frequent Co-authors

Stefan Oscarson(4), Susanne Gustavsson(2), Alexander B. E. Minidis(2), Jörg Holenz(2), Didier Rotticci(2), Per I. Arvidsson(2), Stefan von Berg(2), Johanna Fälting(2), Karin J. Sterky(2), Juliette Janson(1), Colin Ray(1), Susanne Rosqvist(1), Linda I. Nilsson(1), Johan Lundkvist(1), Matías Funes Maldonado(1), Fanny Bjarnemark(1), Mats Svensson(1), Jens Åhman(1), Britt‐Marie Swahn(1), Jacob Kihlström(1)