Jessica Bagel

University of North Carolina at Chapel Hill — United States

Medicine · Health Sciences

19h-index1.3kcitations40works0.52yr avg
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Research Topics

Lysosomal Storage Disorders Research(22), Virus-based gene therapy research(20), Herpesvirus Infections and Treatments(6), RNA regulation and disease(6), Adenosine and Purinergic Signaling(4)

Publications40 total

Increased Gut Microbiota Diversity in Patients With Retinitis Pigmentosa and Implications for Disease Phenotypes and Progression.
UNC Libraries·2026Open Access
Increased Gut Microbiota Diversity in Patients With Retinitis Pigmentosa and Implications for Disease Phenotypes and Progression
Investigative Ophthalmology & Visual Science·2026Open Access
Effect of a Supplement Containing Probiotics, Prebiotics, and Yeast Extract on Gut Inflammation, Microbiota, and Cytokines in Healthy Dogs
Pets·2026Open Access
Increased Gut Microbiota Diversity in Patients With Retinitis Pigmentosa and Implications for Disease Phenotypes and Progression.
Open MIND·2026
Adeno-associated vector corneal gene therapy reverses corneal clouding in a feline model of mucopolysaccharidosis VI
UNC Libraries·2025Open Access
Adeno-associated vector corneal gene therapy reverses corneal clouding in a feline model of mucopolysaccharidosis VI
PLoS ONE·2025Open Access
Age-sensitive response of systemic AAV-mediated gene therapy in a newly characterized feline model of mucolipidosis II
Molecular Therapy·2025· 1 citedOpen Access
Widespread correction of brain pathology in feline alpha-mannosidosis by dose escalation of intracisternal AAV vector injection
Molecular Therapy — Methods & Clinical Development·2024· 3 citedOpen Access
Combination HSCT and intravenous AAV-mediated gene therapy in a canine model proves pivotal for translation of Krabbe disease therapy
Molecular Therapy·2023· 10 citedOpen Access
Transduction characteristics of alternative adeno-associated virus serotypes in the cat brain by intracisternal delivery
Molecular Therapy — Methods & Clinical Development·2022· 6 citedOpen Access
Efficacy and Safety of a Krabbe Disease Gene Therapy
Human Gene Therapy·2022· 48 citedOpen Access
Krabbe disease successfully treated via monotherapy of intrathecal gene therapy
Journal of Clinical Investigation·2020· 67 citedOpen Access
Global CNS correction in a large brain model of human alpha-mannosidosis by intravascular gene therapy
Brain·2020· 26 citedOpen Access
Intrastromal Gene Therapy Prevents and Reverses Advanced Corneal Clouding in a Canine Model of Mucopolysaccharidosis I
Molecular Therapy·2020· 32 citedOpen Access
Cerebrospinal fluid and serum glycosphingolipid biomarkers in canine globoid cell leukodystrophy (Krabbe Disease)
Molecular and Cellular Neuroscience·2019· 22 citedOpen Access
Pharmacokinetics and distribution of 2‐hydroxypropyl‐β‐cyclodextrin following a single intrathecal dose to cats
Journal of Inherited Metabolic Disease·2019· 8 citedOpen Access
LC3 Immunostaining in the Inferior Olivary Nuclei of Cats With Niemann-Pick Disease Type C1 Is Associated With Patterned Purkinje Cell Loss
Journal of Neuropathology & Experimental Neurology·2018· 7 citedOpen Access
AAVrh10 Gene Therapy Ameliorates Central and Peripheral Nervous System Disease in Canine Globoid Cell Leukodystrophy (Krabbe Disease)
Human Gene Therapy·2018· 90 citedOpen Access
Evaluation of Intrathecal Routes of Administration for Adeno-Associated Viral Vectors in Large Animals
Human Gene Therapy·2017· 146 citedOpen Access
Clinical, electrophysiological, and biochemical markers of peripheral and central nervous system disease in canine globoid cell leukodystrophy (<scp>K</scp>rabbe's disease)
Journal of Neuroscience Research·2016· 25 citedOpen Access
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Frequent Co-authors

Charles H. Vite(27), Patricia O’Donnell(18), Gary P. Swain(13), Brittney L. Gurda(10), Maria Prociuk(9), Tracey Sikora(9), Mark E. Haskins(9), James M. Wilson(9), Daniel S. Ory(9), Allison M. Bradbury(9), Therese Ruane(8), Peter Bell(8), Yanqing Zhu(8), Christian Hinderer(7), Patricia A. O’Donnell(7), John H. Wolfe(7), Jean‐Pierre Louboutin(5), Margret L. Casal(5), G. Diane Shelton(5), Sea Young Yoon(5)