Brittney L. Gurda

Biochemistry, Genetics and Molecular Biology · Life Sciences

27h-index2.4kcitations50works0.52yr avg
OpenAlex↗ORCID↗Google Scholar↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Virus-based gene therapy research(39), Viral Infectious Diseases and Gene Expression in Insects(14), Lysosomal Storage Disorders Research(13), Viral gastroenteritis research and epidemiology(7), Viral Infections and Immunology Research(6)

Publications50 total

Correction for Gurda et al., “Mapping a Neutralizing Epitope onto the Capsid of Adeno-Associated Virus Serotype 8”
Journal of Virology·2025· 1 citedOpen Access
656P AAV gene therapy in the Pompe canine model demonstrates correction of the muscle and CNS disorder with immune tolerance to human GAA.
Neuromuscular Disorders·2024
Pharmacokinetics and distribution of 2‐hydroxypropyl‐β‐cyclodextrin following a single intrathecal dose to cats
Journal of Inherited Metabolic Disease·2019· 8 citedOpen Access
Large animal models contribute to the development of therapies for central and peripheral nervous system dysfunction in patients with lysosomal storage diseases
Human Molecular Genetics·2019· 30 citedOpen Access
In Situ Hybridization for Detection of AAV-Mediated Gene Expression
Methods in molecular biology·2019· 8 citedOpen Access
LC3 Immunostaining in the Inferior Olivary Nuclei of Cats With Niemann-Pick Disease Type C1 Is Associated With Patterned Purkinje Cell Loss
Journal of Neuropathology & Experimental Neurology·2018· 7 citedOpen Access
Canine and Feline Models of Human Genetic Diseases and Their Contributions to Advancing Clinical Therapies
.
PubMed·2017· 34 cited
Wnt10b and Dkk-1 gene therapy differentially influenced trabecular bone architecture, soft tissue integrity, and osteophytosis in a skeletally mature rat model of osteoarthritis
Connective Tissue Research·2016· 12 citedOpen Access
Cerebrospinal Fluid Calbindin D Concentration as a Biomarker of Cerebellar Disease Progression in Niemann-Pick Type C1 Disease
Journal of Pharmacology and Experimental Therapeutics·2016· 40 citedOpen Access
611. Promoter Evaluation of AAV Gene Therapy in the Central Nervous System for Feline Niemann-Pick Type C Disease
Molecular Therapy·2016Open Access
Delivery and evaluation of recombinant adeno‐associated viral vectors in the equine distal extremity for the treatment of laminitis
Equine Veterinary Journal·2015· 8 citedOpen Access
Evaluation of AAV-mediated Gene Therapy for Central Nervous System Disease in Canine Mucopolysaccharidosis VII
Molecular Therapy·2015· 84 citedOpen Access
Neonatal Systemic AAV Induces Tolerance to CNS Gene Therapy in MPS I Dogs and Nonhuman Primates
Molecular Therapy·2015· 83 citedOpen Access
A Review of Gene Therapy in Canine and Feline Models of Lysosomal Storage Disorders
Human Gene Therapy Clinical Development·2015· 34 citedOpen Access
Adeno-associated virus vector-mediated gene therapy can effectively treat CNS and cardiac lesions and induce immune tolerance to the therapeutic enzyme in large animal models of mucopolysaccharidosis type I
Molecular Genetics and Metabolism·2015
Evaluating the impact of systemic AAV9.cIDUA administration on brain pathology in MPS I dogs
Molecular Genetics and Metabolism·2015· 1 cited
Intrathecal injection of lentiviral vector results in high expression in the brain of mucopolysaccharidosis VII dogs but the pattern of expression is different than for AAV9 or AAV-rh10
Molecular Genetics and Metabolism·2015
A review of gene therapy in canine and feline models of lysosomal storage disorders
Human Gene Therapy Clinical Development·2015· 5 cited
Structure of an Enteric Pathogen, Bovine Parvovirus
Journal of Virology·2014· 53 citedOpen Access
Adeno-Associated Virus Serotype 1 (AAV1)- and AAV5-Antibody Complex Structures Reveal Evolutionary Commonalities in Parvovirus Antigenic Reactivity
Journal of Virology·2014· 70 citedOpen Access
page 1 of 3Next →

Frequent Co-authors

Mavis Agbandje‐McKenna(25), Robert McKenna(18), James M. Wilson(15), Mark E. Haskins(13), Nicholas Muzyczka(12), Charles H. Vite(12), Peter Bell(10), Jessica Bagel(10), Sergei Zolotukhin(9), Patricia O’Donnell(9), Yanqing Zhu(8), Timothy S. Baker(7), Tracey Sikora(7), Therese Ruane(7), Hyun-Joo Nam(6), Barry J. Byrne(6), L. Govindasamy(6), George Aslanidi(5), Michael A. DiMattia(5), Norman H. Olson(5)