George Aslanidi

University of Minnesota — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

29h-index3.0kcitations98works5.82yr avg
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Research Topics

Virus-based gene therapy research(63), RNA Interference and Gene Delivery(31), Viral Infectious Diseases and Gene Expression in Insects(25), CRISPR and Genetic Engineering(19), Immunotherapy and Immune Responses(13)

Publications98 total

A synthetic platform for developing recombinant adeno‐associated virus type 8 producer cell lines
Biotechnology Progress·2025· 3 citedOpen Access
Consecutive Affinity and Ion-Exchange Chromatography for AAV9 Vectors Purification
Biomedicines·2025· 8 citedOpen Access
Insights in AAV-mediated antigen-specific immunity and a strategy for AAV vaccine dose reduction through AAV-extracellular vesicle association
Molecular Therapy — Methods & Clinical Development·2024· 3 citedOpen Access
AAV-DJ is superior to AAV9 for targeting brain and spinal cord, and de-targeting liver across multiple delivery routes in mice
Journal of Translational Medicine·2024· 15 citedOpen Access
AAV-DJ is Superior to AAV9 for Targeting Brain and Spinal Cord, and De-Targeting Liver Across Multiple Delivery Routes in Mice
2024Open Access
Multiparametric domain insertional profiling of adeno-associated virus VP1
Molecular Therapy — Methods & Clinical Development·2023· 13 citedOpen Access
Bioengineered Hybrid Rep 2/6 Gene Improves Encapsulation of a Single-Stranded Expression Cassette into AAV6 Vectors
Genes·2023· 3 citedOpen Access
Extracellular vesicles enhance pulmonary transduction of stably associated adeno‐associated virus following intratracheal administration
Journal of Extracellular Vesicles·2023· 15 citedOpen Access
Multiparametric domain insertional profiling of Adeno-Associated Virus VP1
2023· 3 citedOpen Access
Multiplexing AAV Serotype-Specific Neutralizing Antibodies in Preclinical Animal Models and Humans
Biomedicines·2023· 4 citedOpen Access
Tumor antigen-loaded AAV vaccine drives protective immunity in a melanoma animal model
Molecular Therapy — Methods & Clinical Development·2023· 26 citedOpen Access
Enhanced Transgene Expression from Recombinant Single-Stranded D-Sequence-Substituted Adeno-Associated Virus Vectors in Human Cell Lines In Vitro and in Murine Hepatocytes In Vivo
UNC Libraries·2020· 2 citedOpen Access
Neutrophil elastase promotes macrophage cell adhesion and cytokine production through the integrin-Src kinases pathway
Scientific Reports·2020· 63 citedOpen Access
Intra-tracheal delivery of AAV6 vectors results in sustained transduction in murine lungs without genomic integration
Gene·2020· 12 citedOpen Access
786 A master regulator function of hairless in skin homeostasis and immune regulation
Journal of Investigative Dermatology·2020
Modifiers of Adeno-Associated Virus-Mediated Gene Expression in Implication for Serotype-Universal Neutralizing Antibody Assay
Human Gene Therapy·2020· 18 citedOpen Access
An AAV6-based multi-antigen vaccine for treatment of murine melanoma
The Journal of Immunology·2020
Development of AAV6-based vaccine with prime-boost capacity by using exosome-protected viral particles
The Journal of Immunology·2020· 1 cited
An Engineered AAV6-Based Vaccine Induces High Cytolytic Anti-Tumor Activity by Directly Targeting DCs and Improves Ag Presentation
Molecular Therapy — Oncolytics·2019· 30 citedOpen Access
Abstract 1467: Bioengineering AAV6 vector-based vaccine for cancer treatment
Clinical Research (Excluding Clinical Trials)·2019
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Frequent Co-authors

Arun Srivastava(20), Chen Ling(18), Sergei Zolotukhin(13), Mavis Agbandje‐McKenna(10), Giridhara R. Jayandharan(8), Nicholas Muzyczka(7), Changquan Ling(7), Yuan Lu(6), Brittney L. Gurda(5), Robert McKenna(5), Barry J. Byrne(5), Kim Van Vliet(5), Baozheng Li(5), Wenqin Ma(5), Zhong Li(5), Angela Rivers(5), Karina Krotova(5), Hyun-Joo Nam(4), Martha Campbell‐Thompson(4), Sanford L. Boye(4)