Guijia He

Biochemistry, Genetics and Molecular Biology · Life Sciences

7h-index218citations12works0.02yr avg
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Research Topics

Protease and Inhibitor Mechanisms(4), Virus-based gene therapy research(3), Viral gastroenteritis research and epidemiology(3), Respiratory viral infections research(3), Neutrophil, Myeloperoxidase and Oxidative Mechanisms(2)

Publications12 total

영화 매출 예측 성능 향상을 위한 경쟁 분석
KIPS Transactions on Software and Data Engineering·2017Open Access
ChemInform Abstract: Inhibition of Noroviruses by Piperazine Derivatives.
ChemInform·2012
Inhibition of noroviruses by piperazine derivatives
Bioorganic & Medicinal Chemistry Letters·2011· 46 citedOpen Access
Potent inhibition of Norwalk virus by cyclic sulfamide derivatives
Bioorganic & Medicinal Chemistry·2011· 29 citedOpen Access
Design, synthesis, and evaluation of inhibitors of Norwalk virus 3C protease
Bioorganic & Medicinal Chemistry Letters·2011· 54 cited
Dual function inhibitors of relevance to chronic obstructive pulmonary disease
Bioorganic & Medicinal Chemistry Letters·2010· 7 citedOpen Access
Design, Synthesis, and In Vitro Evaluation of Potential West Nile Virus Protease Inhibitors Based on the 1-Oxo-1,2,3,4-tetrahydroisoquinoline and 1-Oxo-1,2-dihydroisoquinoline Scaffolds
Journal of Combinatorial Chemistry·2010· 30 cited
Effects of structure on inhibitory activity in a series of mechanism-based inhibitors of human neutrophil elastase
Bioorganic & Medicinal Chemistry·2010· 5 cited
Inhibitors of human neutrophil elastase based on a highly functionalized N-amino-4-imidazolidinone scaffold
European Journal of Medicinal Chemistry·2010· 7 citedOpen Access
Utilization of the 1,2,3,5-thiatriazolidin-3-one 1,1-dioxide scaffold in the design of potential inhibitors of human neutrophil proteinase 3
Bioorganic & Medicinal Chemistry·2009· 21 citedOpen Access
Potential inhibitors of COPD-relevant serine proteases based on the N-amino-4-imidazolidinone scaffold
Holmes Museum Of Anthropology (Wichita State University)·2009Open Access
Mechanism-based inhibitors of serine proteases with high selectivity through optimization of S′ subsite binding
Bioorganic & Medicinal Chemistry·2009· 19 citedOpen Access

Frequent Co-authors

William C. Groutas(10), Dengfeng Dou(9), Kevin R. Alliston(6), Sridhar Aravapalli(4), Sivakoteswara Rao Mandadapu(4), Gerald H. Lushington(4), Yunjeong Kim(4), Kyeong‐Ok Chang(4), Kok-Chuan Tiew(2), Yi Li(2), Liuqing Wei(2), Mallikarjuna Reddy Gunnam(1), Prasanth Viwanathan(1), Li Yi(1), Joshua Brown-Clay(1), Radhakrishnan Padmanabhan(1), Zhong Lai(1), David M. Eichhorn(1), Rongze Kuang(1), Qingfong Fu(1)