Hugo Rego Campello

California Institute of Technology — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

6h-index179citations17works0.02yr avg
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Research Topics

Nicotinic Acetylcholine Receptors Study(9), Receptor Mechanisms and Signaling(6), Crystallization and Solubility Studies(4), X-ray Diffraction in Crystallography(4), Synthesis and Biological Evaluation(4)

Publications17 total

Human α6β4 Nicotinic Acetylcholine Receptor: Heterologous Expression and Agonist Behavior Provide Insights into the Immediate Binding Site
Molecular Pharmacology·2023· 4 cited
Correction: Fluorescence activation mechanism and imaging of drug permeation with new sensors for smoking-cessation ligands
eLife·2022· 3 citedOpen Access
Characterization of Binding Site Interactions and Selectivity Principles in the α3β4 Nicotinic Acetylcholine Receptor
Journal of the American Chemical Society·2022· 16 cited
Author response: Fluorescence activation mechanism and imaging of drug permeation with new sensors for smoking-cessation ligands
2021Open Access
Fluorescence Activation Mechanism and Imaging of Drug Permeation with New Sensors for Smoking-Cessation Ligands
2021· 2 citedOpen Access
The thermodynamic profile and molecular interactions of a C(9)-cytisine derivative-binding acetylcholine-binding protein from <i>Aplysia californica</i>
Acta Crystallographica Section F Structural Biology Communications·2020· 2 citedOpen Access
Probing Binding Interactions of Cytisine Derivatives to the α4β2 Nicotinic Acetylcholine Receptor
Journal of the American Chemical Society·2019· 32 cited
Identification of the Initial Steps in Signal Transduction in the α4β2 Nicotinic Receptor: Insights from Equilibrium and Nonequilibrium Simulations
Structure·2019· 42 citedOpen Access
Iridium-Catalysed C–H Borylation of 2-Pyridones; Bisfunctionalisation of CC4
Synthesis·2018· 6 cited
Unlocking Nicotinic Selectivity via Direct C‒H Functionalization of (−)-Cytisine
Chem·2018· 42 citedOpen Access
CCDC 1840056: Experimental Crystal Structure Determination
The Cambridge Structural Database·2018Open Access
(−)-Cytisine: Access to a stereochemically defined and functionally flexible piperidine scaffold
Organic & Biomolecular Chemistry·2018· 7 citedOpen Access
CCDC 1840055: Experimental Crystal Structure Determination
The Cambridge Structural Database·2018Open Access
CCDC 1840054: Experimental Crystal Structure Determination
The Cambridge Structural Database·2018Open Access
C(5) Site-Selective Functionalization of (<i>S</i>)-Cotinine
The Journal of Organic Chemistry·2017· 1 cited
Asymmetric Reduction of Lactam-Based β-Aminoacrylates. Synthesis of Heterocyclic β<sup>2</sup>-Amino Acids
Organic Letters·2016· 22 cited
CCDC 1456322: Experimental Crystal Structure Determination
The Cambridge Structural Database·2016Open Access

Frequent Co-authors

Timothy Gallagher(12), Henry A. Lester(6), Dennis A. Dougherty(6), Timothy Gallagher(5), Worawat Niwetmarin(5), Annet E. M. Blom(4), Hailey J. Knox(4), Varinder K. Aggarwal(4), Aaron L. Nichols(3), Zack Blumenfeld(3), Chengcheng Fan(3), Laura Luebbert(3), Bruce Cohen(3), Jonathan S. Marvin(3), Philip M. Borden(3), Charlene H. Kim(3), Anand K. Muthusamy(3), Amol V. Shivange(3), Jonathan H Wang(3), Loren L. Looger(3)