B. Kevin Park

Medicine · Health Sciences

13h-index609citations19works0.02yr avg
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Research Topics

Drug Transport and Resistance Mechanisms(7), Pharmacogenetics and Drug Metabolism(5), Drug-Induced Hepatotoxicity and Protection(5), Pharmacological Effects and Toxicity Studies(4), Mitochondrial Function and Pathology(3)

Publications19 total

A study on ecotourism awareness using big data analysis: Focusing on the COVID-19 pandemic period
International Journal of Tourism and Hospitality Research·2023
Investigating dihydroorotate dehydrogenase inhibitor mediated mitochondrial dysfunction in hepatic in vitro models
Toxicology in Vitro·2021· 15 cited
The utility of a differentiated preclinical liver model, HepaRG cells, in investigating delayed toxicity via inhibition of mitochondrial-replication induced by fialuridine
Toxicology and Applied Pharmacology·2020· 9 citedOpen Access
Safety perspectives on presently considered drugs for the treatment of COVID‐19
British Journal of Pharmacology·2020· 20 citedOpen Access
Differential toxic effects of bile acid mixtures in isolated mitochondria and physiologically relevant HepaRG cells
Toxicology in Vitro·2019· 23 citedOpen Access
Acute Metabolic Switch Assay Using Glucose/Galactose Medium in HepaRG Cells to Detect Mitochondrial Toxicity
Current Protocols in Toxicology·2019· 21 cited
The utility of HepaRG cells for bioenergetic investigation and detection of drug-induced mitochondrial toxicity
Toxicology in Vitro·2018· 42 citedOpen Access
Human OATP1B1 (SLCO1B1) transports sulfated bile acids and bile salts with particular efficiency
Toxicology in Vitro·2018· 13 cited
Kinetic characterization of bile salt transport by human NTCP (SLC10A1)
Toxicology in Vitro·2017· 21 cited
Quantification of Drug-Induced Inhibition of Canalicular Cholyl-l-Lysyl-Fluorescein Excretion From Hepatocytes by High Content Cell Imaging
Toxicological Sciences·2015· 37 citedOpen Access
The utility of HepG2 cells to identify direct mitochondrial dysfunction in the absence of cell death
Toxicology in Vitro·2015· 150 citedOpen Access
Abacavir Forms Novel Cross-Linking Abacavir Protein Adducts in Patients
Chemical Research in Toxicology·2014· 21 cited
Detection of Drug Bioactivation in Vivo: Mechanism of Nevirapine–Albumin Conjugate Formation in Patients
Chemical Research in Toxicology·2013· 45 cited
The elucidation of the mechanisms of bleomycin-induced cytotoxicity in alveolar type II cells in vitro
Toxicology·2011
Characterisation of bleomycin-induced cytotoxicity in mammalian alveolar type II cells
Toxicology·2010
Protein binding and pharmacokinetics of reactive acyl glucuronide drug metabolites
Toxicology·2010
Quantifying the Metabolic Activation of Nevirapine in Patients by Integrated Applications of NMR and Mass Spectrometries
Drug Metabolism and Disposition·2009· 61 citedOpen Access
Functional and toxicological consequences of metabolic bioactivation of methapyrilene via thiophene S-oxidation: Induction of cell defence, apoptosis and hepatic necrosis
Toxicology and Applied Pharmacology·2009· 25 cited
Metabolism of Lamotrigine to a Reactive Arene Oxide Intermediate
Chemical Research in Toxicology·2000· 106 cited

Frequent Co-authors

Amy E. Chadwick(7), Dominic P. Williams(6), Laleh Kamalian(4), Neil French(4), Mario Monshouwer(4), Jan Snoeys(4), James L. Maggs(4), Xiaoli Meng(4), Sophie L. Penman(4), Dean J. Naisbitt(3), Munir Pirmohamed(3), Rosalind E. Jenkins(3), David Back(3), Oisin Douglas(3), Carol Jolly(3), Damir Simic(3), J. Gerry Kenna(3), Amy E. Mercer(3), Richard Weaver(3), Mark Bayliss(2)