Jiří Gut

San Francisco General Hospital — United States

Medicine · Health Sciences

58h-index10.2kcitations198works0.02yr avg
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Research Topics

Malaria Research and Control(79), Synthesis and biological activity(42), Research on Leishmaniasis Studies(31), Synthesis and Biological Evaluation(31), HIV/AIDS drug development and treatment(29)

Publications198 total

Artefenomel Regioisomer RLA-3107 Is a Promising Lead for the Discovery of Next-Generation Endoperoxide Antimalarials
ACS Medicinal Chemistry Letters·2023· 14 citedOpen Access
Antimalarial Trioxolanes with Superior Drug-Like Properties and In Vivo Efficacy
ACS Infectious Diseases·2020· 26 citedOpen Access
Coupling the Antimalarial Cell Penetrating Peptide TP10 to Classical Antimalarial Drugs Primaquine and Chloroquine Produces Strongly Hemolytic Conjugates
Molecules·2019· 18 citedOpen Access
[(7-chloroquinolin-4-yl)amino]acetophenones and their copper(II) derivatives: synthesis, characterization, computational studies and antimalarial activity
PubMed·2019· 2 citedOpen Access
Identification of a potent benzoxaborole drug candidate for treating cryptosporidiosis
Nature Communications·2019· 59 citedOpen Access
Falcipain Inhibitors Based on the Natural Product Gallinamide A Are Potent in Vitro and in Vivo Antimalarials
Journal of Medicinal Chemistry·2019· 32 citedOpen Access
Efficacy of subcutaneous doses and a new oral amorphous solid dispersion formulation of flubendazole on male jirds (Meriones unguiculatus) infected with the filarial nematode Brugia pahangi
PLoS neglected tropical diseases·2019· 14 citedOpen Access
Endoperoxide-8-aminoquinoline hybrids as dual-stage antimalarial agents with enhanced metabolic stability
European Journal of Medicinal Chemistry·2018· 32 cited
Microwave-promoted facile access to 4-aminoquinoline-phthalimides: Synthesis and anti-plasmodial evaluation
European Journal of Medicinal Chemistry·2017· 30 cited
Synthesis, Characterization, Crystal Structure and Antimalarial Activity of (2E)-2-(1-{4-[(7-chloroquinolin-4-yl)amino]phenyl} ethylidene)hydrazine Carbothioamide
LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)·2017
Synthesis, Characterization, Crystal Structure and Antimalarial Activity of (2E)-2-(1-{4-[(7-chloroquinolin-4-yl)amino]phenyl} ethylidene)hydrazine Carbothioamide
Orbital - The Electronic Journal of Chemistry·2017· 2 citedOpen Access
Development of Novel Peptide-Based Michael Acceptors Targeting Rhodesain and Falcipain-2 for the Treatment of Neglected Tropical Diseases (NTDs)
Journal of Medicinal Chemistry·2017· 58 citedOpen Access
4-Aminoquinoline-chalcone/- N -acetylpyrazoline conjugates: Synthesis and antiplasmodial evaluation
European Journal of Medicinal Chemistry·2017· 54 cited
Enantioselective Synthesis and in Vivo Evaluation of Regioisomeric Analogues of the Antimalarial Arterolane
Journal of Medicinal Chemistry·2017· 20 citedOpen Access
Piperazine‐linked 4‐aminoquinoline‐chalcone/ferrocenyl‐chalcone conjugates: Synthesis and antiplasmodial evaluation
Chemical Biology & Drug Design·2017· 26 cited
A potent antimalarial benzoxaborole targets a Plasmodium falciparum cleavage and polyadenylation specificity factor homologue
Nature Communications·2017· 137 citedOpen Access
CCDC 1413401: Experimental Crystal Structure Determination
The Cambridge Structural Database·2017Open Access
4-Aminoquinoline-ferrocenyl-chalcone conjugates: Synthesis and anti-plasmodial evaluation
European Journal of Medicinal Chemistry·2016· 73 cited
Probing the Azaaurone Scaffold against the Hepatic and Erythrocytic Stages of Malaria Parasites
ChemMedChem·2016· 28 cited
Cryptosporidium and Toxoplasma Parasites Are Inhibited by a Benzoxaborole Targeting Leucyl-tRNA Synthetase
Antimicrobial Agents and Chemotherapy·2016· 67 citedOpen Access
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Frequent Co-authors

Philip J. Rosenthal(43), James H. McKerrow(6), Peter J. Smith(6), Kelly Chibale(5), Vipan Kumar(5), Jennifer Legac(5), Joseph L. DeRisi(4), Kelly Chibale(4), Yvonne R. Freund(4), Richard G. Nelson(3), Bhaskar R. Shenai(3), Elizabeth Hansell(3), Patricia S. Doyle(3), Puran Singh Sijwali(3), Eric M. Guantai(3), Julie Lehman(3), Carmen Lategan(3), Fabrice Fekam Boyom(3), Kelly Chibale(3), Carolyn Petersen(3)