Fardos N.M. Naguib

Ain Shams University — Egypt

Biochemistry, Genetics and Molecular Biology · Life Sciences

24h-index1.8kcitations68works1.02yr avg
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Research Topics

Biochemical and Molecular Research(42), Toxoplasma gondii Research Studies(14), Folate and B Vitamins Research(11), Pancreatic and Hepatic Oncology Research(10), HIV/AIDS drug development and treatment(10)

Publications68 total

Automatic Summarization Techniques for Arabic Text;
International journal of intelligent computing and information sciences/International Journal of Intelligent Computing and Information Sciences·2025· 1 citedOpen Access
Enzymes of pyrimidine salvage pathways in intraerythrocytic Plasmodium falciparum
The International Journal of Biochemistry & Cell Biology·2018· 5 cited
Kinetic mechanism of Toxoplasma gondii adenosine kinase and the highly efficient utilization of adenosine
Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology·2015· 5 citedOpen Access
Nucleoside kinases in adult Schistosoma mansoni: Phosphorylation of pyrimidine nucleosides
Molecular and Biochemical Parasitology·2014· 2 cited
Potent combination therapy for human breast tumors with high doses of 5-fluorouracil: remission and lack of host toxicity
Cancer Chemotherapy and Pharmacology·2012· 6 cited
Carbocyclic 6-benzylthioinosine analogues as subversive substrates of Toxoplasma gondii adenosine kinase: Biological activities and selective toxicities
Biochemical Pharmacology·2010· 17 citedOpen Access
Structure–activity relationships of carbocyclic 6-benzylthioinosine analogues as subversive substrates of Toxoplasma gondii adenosine kinase
Bioorganic & Medicinal Chemistry·2010· 18 citedOpen Access
7-Deaza-6-benzylthioinosine analogues as subversive substrate of Toxoplasma gondii adenosine kinase: Activities and selective toxicities
Biochemical Pharmacology·2008· 35 citedOpen Access
Structure−Activity Relationships of 7-Deaza-6-benzylthioinosine Analogues as Ligands of<i>Toxoplasma gondii</i>Adenosine Kinase
Journal of Medicinal Chemistry·2008· 37 citedOpen Access
Suppression of thymidine phosphorylase expression by promoter methylation in human cancer cells lacking enzyme activity
Cancer Chemotherapy and Pharmacology·2007· 8 cited
Suppression of thymidine phosphorylase expression by promoter methylation
Journal of Clinical Oncology·2007
Synthesis, biological evaluation and molecular modeling studies of N6-benzyladenosine analogues as potential anti-toxoplasma agents
Biochemical Pharmacology·2007· 36 citedOpen Access
Modulation of 5-fluorouracil host-toxicity and chemotherapeutic efficacy against human colon tumors by 5-(Phenylthio)acyclouridine, a uridine phosphorylase inhibitor
Cancer Chemotherapy and Pharmacology·2006· 19 cited
6-Benzylthioinosine analogues: Promising anti-toxoplasmic agents as inhibitors of the mammalian nucleoside transporter ENT1 (es)
Biochemical Pharmacology·2005· 20 cited
6-Benzylthioinosine analogues as subversive substrate of Toxoplasma gondii adenosine kinase: Activities and selective toxicities
Biochemical Pharmacology·2005· 25 cited
5-(Phenylthio)acyclouridine: a powerful enhancer of oral uridine bioavailability: relevance to chemotherapy with 5-fluorouracil and other uridine rescue regimens
Cancer Chemotherapy and Pharmacology·2005· 68 cited
Synthesis, Biological Activity and Molecular Modeling of 6-Benzylthioinosine Analogues as Subversive Substrates of<i>Toxoplasma</i><i>g</i><i>ondii</i>Adenosine Kinase
Journal of Medicinal Chemistry·2004· 49 cited
Uptake of Nitrobenzylthioinosine and Purine β- <scp>l</scp> -Nucleosides by Intracellular <i>Toxoplasma gondii</i>
Antimicrobial Agents and Chemotherapy·2003· 31 citedOpen Access
Design and syntheses of focused combinatorial library for lead optimization and SAR studies of NBMPR based subversive substrates of T gondii adenosine kinase
Abstracts of Papers American Chemical Society·2003
ChemInform Abstract: Synthesis of Carbocyclic Orotidine Analogues as Potential Orotidine Decarboxylase Inhibitors.
ChemInform·2002
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Frequent Co-authors

Mahmoud H. el Kouni(41), Omar N. Al Safarjalani(16), Chung K. Chu(11), Sungman Cha(9), Reem H. Rais(9), Raymond P. Panzica(6), Raymond F. Schinazi(6), Max H. Iltzsch(5), Young Ah Kim(5), Shih Hsi Chu(4), Naganna M. Goudgaon(4), Ming Chu(3), Junxing Shi(3), Vincenzo Guarcello(3), Ashoke Sharon(3), Brian A. Otter(3), Osama M. Ashour(3), David R. Nash(3), Mahmoud el Kouni(3), William J. Sullivan(2)