Renina Gale Navarro

University of Sydney — Australia

Biochemistry, Genetics and Molecular Biology · Life Sciences

10h-index382citations15works11.72yr avg
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Research Topics

Virus-based gene therapy research(15), Viral gastroenteritis research and epidemiology(5), Viral Infections and Immunology Research(5), RNA Interference and Gene Delivery(4), CRISPR and Genetic Engineering(4)

Publications15 total

AAVolve: Concatenated long-read deep sequencing enables whole capsid tracking during shuffled AAV library selection
Molecular Therapy — Methods & Clinical Development·2024· 2 citedOpen Access
Harnessing whole human liver ex situ normothermic perfusion for preclinical AAV vector evaluation
Nature Communications·2024· 24 citedOpen Access
Novel AAV variants with improved tropism for human Schwann cells
Molecular Therapy — Methods & Clinical Development·2024· 9 citedOpen Access
Harnessing the power of whole human liver ex situ normothermic perfusion for preclinical AAV vector evaluation
Research Square (Research Square)·2023Open Access
Harnessing the power of whole human liver ex situ normothermic perfusion for preclinical AAV vector evaluation
2023Open Access
Assessment of Pre-Clinical Liver Models Based on Their Ability to Predict the Liver-Tropism of Adeno-Associated Virus Vectors
Human Gene Therapy·2023· 21 citedOpen Access
Characterization of the humanized FRG mouse model and development of an AAV-LK03 variant with improved liver lobular biodistribution
Molecular Therapy — Methods & Clinical Development·2023· 15 citedOpen Access
Assessment of pre-clinical liver models based on their ability to predict the liver-tropism of AAV vectors
2022· 1 citedOpen Access
Adeno‐associated virus serotype 2 capsid variants for improved liver‐directed gene therapy
Hepatology·2022· 21 citedOpen Access
AAV-p40 Bioengineering Platform for Variant Selection Based on Transgene Expression
Human Gene Therapy·2022· 27 citedOpen Access
Novel human liver-tropic AAV variants define transferable domains that markedly enhance the human tropism of AAV7 and AAV8
Molecular Therapy — Methods & Clinical Development·2021· 40 citedOpen Access
Single amino acid insertion allows functional transduction of murine hepatocytes with human liver tropic AAV capsids
Molecular Therapy — Methods & Clinical Development·2021· 28 citedOpen Access
Restoring the natural tropism of AAV2 vectors for human liver
Science Translational Medicine·2020· 56 cited
Attenuation of Heparan Sulfate Proteoglycan Binding Enhances In Vivo Transduction of Human Primary Hepatocytes with AAV2
Molecular Therapy — Methods & Clinical Development·2020· 44 citedOpen Access
High-Throughput <i>In Vitro</i> , <i>Ex Vivo,</i> and <i>In Vivo</i> Screen of Adeno-Associated Virus Vectors Based on Physical and Functional Transduction
Human Gene Therapy·2020· 94 citedOpen Access

Frequent Co-authors

Leszek Lisowski(15), Erhua Zhu(14), Ian E. Alexander(14), Adrian Westhaus(12), Marti Cabanes‐Creus(12), Grober Baltazar(9), Suzanne Scott(9), Sophia H.Y. Liao(8), Adrian J. Thrasher(7), Matthieu Drouyer(6), Giorgia Santilli(6), Maddison Knight(5), Natalie A. Twine(5), Deborah Nazareth(5), Gloria González‐Aseguinolaza(5), Geoffrey W. McCaughan(4), Anais K. Amaya(4), Ramon Roca-Pinilla(4), Jessica Merjane(4), Kimberley L. Dilworth(3)