Suzanne Scott

Commonwealth Scientific and Industrial Research Organisation — Australia

Biochemistry, Genetics and Molecular Biology · Life Sciences

15h-index847citations37works6.12yr avg
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Research Topics

Virus-based gene therapy research(14), CRISPR and Genetic Engineering(7), RNA Interference and Gene Delivery(5), Nicotinic Acetylcholine Receptors Study(5), Advanced Fluorescence Microscopy Techniques(4)

Publications36 total

The seven symptoms that can delay brain tumour diagnosis – and why early detection matters
2025
Highly Efficient Functional Editing of the Native Ornithine Transcarbamylase Locus by Targeted Integration with Phenotype Correction and Restoration of Physiological Patterns of Gene Expression
2025Open Access
Tailoring capsid-directed evolution technology for improved AAV-mediated CAR-T generation
Molecular Therapy·2024· 4 cited
AAVolve: Concatenated long-read deep sequencing enables whole capsid tracking during shuffled AAV library selection
Molecular Therapy — Methods & Clinical Development·2024· 2 citedOpen Access
Enhanced AAV transduction across preclinical CNS models: A comparative study in human brain organoids with cross-species evaluations
Molecular Therapy — Nucleic Acids·2024· 13 citedOpen Access
Novel AAV variants with improved tropism for human Schwann cells
Molecular Therapy — Methods & Clinical Development·2024· 9 citedOpen Access
Development of CNS tropic AAV1-like variants with reduced liver-targeting following systemic administration in mice
Molecular Therapy·2024· 15 citedOpen Access
Development of new adeno-associated virus capsid variants for targeted gene delivery to human cardiomyocytes
Molecular Therapy — Methods & Clinical Development·2023· 23 citedOpen Access
Assessment of Pre-Clinical Liver Models Based on Their Ability to Predict the Liver-Tropism of Adeno-Associated Virus Vectors
Human Gene Therapy·2023· 21 citedOpen Access
Characterization of the humanized FRG mouse model and development of an AAV-LK03 variant with improved liver lobular biodistribution
Molecular Therapy — Methods & Clinical Development·2023· 15 citedOpen Access
Assessment of pre-clinical liver models based on their ability to predict the liver-tropism of AAV vectors
2022· 1 citedOpen Access
A bioinformatic pipeline for simulating viral integration data
Data in Brief·2022· 1 citedOpen Access
Isling: A Tool for Detecting Integration of Wild-Type Viruses and Clinical Vectors
Journal of Molecular Biology·2021· 5 citedOpen Access
Novel human liver-tropic AAV variants define transferable domains that markedly enhance the human tropism of AAV7 and AAV8
Molecular Therapy — Methods & Clinical Development·2021· 40 citedOpen Access
Cloud-based Machine Learning for Genome Engineering
2021
How computational science and data-driven health decisions help in the fight against COVID-19
2021
GT-Scan suite
2021
Single amino acid insertion allows functional transduction of murine hepatocytes with human liver tropic AAV capsids
Molecular Therapy — Methods & Clinical Development·2021· 28 citedOpen Access
Resistance to compressive force in continuous chelation
Australian Endodontic Journal·2020· 7 cited
Restoring the natural tropism of AAV2 vectors for human liver
Science Translational Medicine·2020· 56 cited
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Frequent Co-authors

Ian E. Alexander(14), Leszek Lisowski(14), Erhua Zhu(11), Natalie A. Twine(10), Adrian Westhaus(9), Renina Gale Navarro(9), Marti Cabanes‐Creus(8), Sophia H.Y. Liao(8), Matthieu Drouyer(7), Adrian J. Thrasher(6), Denis C. Bauer(6), Grober Baltazar(5), Giorgia Santilli(5), Samantha L. Ginn(5), Zhengyi Yang(5), Peter Haslehurst(5), Nigel J. Emptage(5), Kishan Dholakia(5), A.R. Aricescu(4), Claus V. Hallwirth(4)