John Coadwell

Babraham Institute — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

26h-index4.2kcitations42works0.02yr avg
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Research Topics

Protein Kinase Regulation and GTPase Signaling(11), Cellular transport and secretion(10), PI3K/AKT/mTOR signaling in cancer(8), Monoclonal and Polyclonal Antibodies Research(7), Glycosylation and Glycoproteins Research(6)

Publications42 total

ARAP3 binding to phosphatidylinositol-(3,4,5)-trisphosphate depends on N-terminal tandem PH domains and adjacent sequences
Cellular Signalling·2009· 20 cited
Light chain-deficient mice produce novel multimeric heavy-chain-only IgA by faulty class switching
International Immunology·2009· 5 citedOpen Access
Emerging findings from studies of phospholipase D in model organisms (and a short update on phosphatidic acid effectors)
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids·2009· 45 cited
Evolutionary divergence of valosin‐containing protein/cell division cycle protein 48 binding interactions among endoplasmic reticulum‐associated degradation proteins
FEBS Journal·2009· 44 citedOpen Access
The Equatorial Subsegment in Mammalian Spermatozoa Is Enriched in Tyrosine Phosphorylated Proteins1
Biology of Reproduction·2008· 54 citedOpen Access
PA binding of phosphatidylinositol 4-phosphate 5-kinase
Advances in Enzyme Regulation·2007· 31 cited
Eleven new putative aminergic G-protein coupled receptors from Amphioxus (Branchiostoma floridae): identification, sequence analysis and phylogenetic relationship
Invertebrate Neuroscience·2007· 12 cited
Gβγs and the Ras binding domain of p110γ are both important regulators of PI3Kγ signalling in neutrophils
Nature Cell Biology·2006· 169 cited
p84, a New Gβγ-Activated Regulatory Subunit of the Type IB Phosphoinositide 3-Kinase p110γ
Current Biology·2005· 164 citedOpen Access
An abundant placental transcript containing an IAP-LTR is allelic to mouse pregnancy-specific glycoprotein 23 (Psg23): cloning and genetic analysis
Gene·2003· 16 cited
Hierarchy of Membrane-targeting Signals of Phospholipase D1 Involving Lipid Modification of a Pleckstrin Homology Domain
Journal of Biological Chemistry·2002· 30 citedOpen Access
Identification of ARAP3, a Novel PI3K Effector Regulating Both Arf and Rho GTPases, by Selective Capture on Phosphoinositide Affinity Matrices
Molecular Cell·2002· 299 citedOpen Access
FENS-1 and DFCP1 are FYVE domain-containing proteins with distinct functions in the endosomal and Golgi compartments
Journal of Cell Science·2001· 115 cited
Isolation and characterization of two novel A20-like proteins
Biochemical Journal·2001· 82 citedOpen Access
Isolation and characterization of two novel A20-like proteins
Biochemical Journal·2001· 74 cited
PtdIns(3)P regulates the neutrophil oxidase complex by binding to the PX domain of p40phox
Nature Cell Biology·2001· 397 cited
Studies on transcriptional regulation of the mucosal T‐cell integrin αEβ7 (CD103)
Immunology·2001· 76 citedOpen Access
Identification of phosphoinositide-binding proteins by using phosphoinositide-coupled affinity matrices
Biochemical Society Transactions·2001
Structural Organization of the Mouse Phosphatidylinositol 3-Kinase p110d Gene
Biochemical and Biophysical Research Communications·2001· 5 cited
DAPP1 undergoes a PI 3-kinase-dependent cycle of plasma-membrane recruitment and endocytosis upon cell stimulation
Current Biology·2000· 41 citedOpen Access
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Frequent Co-authors

Len Stephens(12), Phillip T. Hawkins(11), Karen E. Anderson(8), Paul Tempst(7), Maria Manifava(7), Nicholas T. Ktistakis(7), D. Beale(7), Hediye Erdjument‐Bromage(6), Keith Davidson(6), Roy Jones(6), Chris D. Ellson(5), Jan Willem Thuring(5), Ze‐Yi Lim(5), Andrew B. Holmes(4), A. Eguinoa(4), Peter J. Kilshaw(4), Gavin F. Painter(3), Matthew A. Cooper(3), S H Ridley(3), Peter Lipp(3)