Karen E. Anderson

Babraham Institute — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

69h-index17.3kcitations216works1.12yr avg
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Research Topics

PI3K/AKT/mTOR signaling in cancer(36), Protein Kinase Regulation and GTPase Signaling(28), Cellular transport and secretion(20), Receptor Mechanisms and Signaling(15), Neutrophil, Myeloperoxidase and Oxidative Mechanisms(14)

Publications216 total

Oncometabolite 5-IP7 inhibits inositol 5-phosphatase to license E-cadherin endocytosis
Nature Chemical Biology·2025· 1 cited
FGF-induced phospholipase Cγ signaling regulates lacrimal gland branching by competing with PI3K in phosphoinositide metabolism
Cell Reports·2025· 1 citedOpen Access
Liver gene expression and its rewiring in hepatic steatosis are controlled by PI3Kα-dependent hepatocyte signaling
PLoS Biology·2025· 1 citedOpen Access
Automated Fracture Detection and Classification Using Siamese Neural Networks
2024
Use of Baseline Inflammatory Markers to Predict Toxicities Among Relapsed/Refractory Multiple Myeloma Patients Receiving Ambulatory Teclistamab and Talquetamab
Blood·2024· 1 cited
CDS2 expression regulates <i>de novo</i> phosphatidic acid synthesis
Biochemical Journal·2024· 4 citedOpen Access
H001 How clinical trials and community outreach contribute to patient care outcomes in Huntington’s disease a 2 year follow up
2024Open Access
The LCLAT1/LYCAT acyltransferase is required for EGF-mediated phosphatidylinositol-3,4,5-trisphosphate generation and Akt signaling
Molecular Biology of the Cell·2024· 2 citedOpen Access
Phospholipase Cγ regulates lacrimal gland branching by competing with PI3K in phosphoinositide metabolism
2024Open Access
ASO Visual Abstract: Robot-Assisted Pelvic Dissection for Enlarged Lymph Nodes in Melanoma Improves Recovery with Equivalent Oncological Outcomes to Open Pelvic Dissection
Annals of Surgical Oncology·2024
p110α-dependent hepatocyte signaling is critical for liver gene expression and its rewiring in MASLD
2024Open Access
Robot-Assisted Pelvic Dissection for Enlarged Lymph Nodes in Melanoma Improves Recovery with Equivalent Oncological Outcomes to Open Pelvic Dissection
Annals of Surgical Oncology·2024· 3 citedOpen Access
PLEKHS1 drives PI3Ks and remodels pathway homeostasis in PTEN-null prostate
Molecular Cell·2023· 12 citedOpen Access
A small-molecule PI3Kα activator for cardioprotection and neuroregeneration
Nature·2023· 138 citedOpen Access
PLEKHS1 drives PI3Ks and remodels pathway homeostasis in PTEN-null prostate
2023Open Access
Figure S3 from SGK1 Is a Critical Component of an AKT-Independent Pathway Essential for PI3K-Mediated Tumor Development and Maintenance
2023Open Access
Figure S5 from SGK1 Is a Critical Component of an AKT-Independent Pathway Essential for PI3K-Mediated Tumor Development and Maintenance
2023Open Access
Figure S2 from SGK1 Is a Critical Component of an AKT-Independent Pathway Essential for PI3K-Mediated Tumor Development and Maintenance
2023Open Access
Suppl. Fig. Legends from SGK1 Is a Critical Component of an AKT-Independent Pathway Essential for PI3K-Mediated Tumor Development and Maintenance
2023Open Access
Figure S2 from SGK1 Is a Critical Component of an AKT-Independent Pathway Essential for PI3K-Mediated Tumor Development and Maintenance
2023Open Access
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Frequent Co-authors

Phillip T. Hawkins(18), Len Stephens(17), Keith Davidson(7), Anton Reiner(6), George D. Yancopoulos(6), Chris D. Ellson(6), John Coadwell(5), Roger L. Albin(5), Stanley J. Wiegand(5), Hediye Erdjument‐Bromage(4), Andrew B. Holmes(4), Paul Tempst(4), Gavin Thurston(4), Shaun P. Jackson(4), Suhasini Kulkarni(4), Mark W. Sleeman(4), John B. Penney(4), Stanley J. Wiegand(4), Cindy L. Yap(3), Jan Willem Thuring(3)