Yafeng Xue

Xi'an Physical Education University — China

Materials Science · Physical Sciences

33h-index3.3kcitations77works0.22yr avg
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Research Topics

Enzyme Structure and Function(9), Enzyme function and inhibition(9), Blood Coagulation and Thrombosis Mechanisms(7), Psoriasis: Treatment and Pathogenesis(6), Synthesis and Catalytic Reactions(6)

Publications77 total

A systematic evaluation of musculoskeletal injuries in mixed martial arts athletes: a meta-analysis
The Journal of Sports Medicine and Physical Fitness·2026
Design of Bicyclic Peptide Tandems Mimicking the Homodimeric GDF15 Protein to Inhibit GDF15–GFRaL–RET Complex Cell Signaling
Journal of Medicinal Chemistry·2025· 1 cited
Generation of a potent & selective series of IRAK4 inhibitors based on a structure based, hybridization approach
Bioorganic & Medicinal Chemistry·2025
IRAK4 in complex with inhibitor
2025
Strategies for Core Strength Training in Free Combat Teaching
Journal of Contemporary Educational Research·2024Open Access
Identification and optimisation of a pyrimidopyridone series of IRAK4 inhibitors
Bioorganic & Medicinal Chemistry·2022· 5 citedOpen Access
AZD0284, a Potent, Selective, and Orally Bioavailable Inverse Agonist of Retinoic Acid Receptor-Related Orphan Receptor C2
Journal of Medicinal Chemistry·2021· 24 citedOpen Access
Improving metabolic stability and removing aldehyde oxidase liability in a 5-azaquinazoline series of IRAK4 inhibitors
Bioorganic & Medicinal Chemistry·2020· 10 citedOpen Access
Phenotypic Screen with the Human Secretome Identifies FGF16 as Inducing Proliferation of iPSC-Derived Cardiac Progenitor Cells
International Journal of Molecular Sciences·2019· 25 citedOpen Access
Discovery of a Series of 5-Azaquinazolines as Orally Efficacious IRAK4 Inhibitors Targeting MyD88<sup>L265P</sup> Mutant Diffuse Large B Cell Lymphoma
Journal of Medicinal Chemistry·2019· 20 citedOpen Access
Discovery of Potent and Orally Bioavailable Inverse Agonists of the Retinoic Acid Receptor-Related Orphan Receptor C2
ACS Medicinal Chemistry Letters·2019· 18 cited
Ligand complex of RORg LBD
2019· 6 citedOpen Access
Potent and Orally Bioavailable Inverse Agonists of RORγt Resulting from Structure-Based Design
Journal of Medicinal Chemistry·2018· 37 citedOpen Access
Optimization of permeability in a series of pyrrolotriazine inhibitors of IRAK4
Bioorganic & Medicinal Chemistry·2018· 23 citedOpen Access
Ligand complex of RORg LBD
2017
Structure‐Based Drug Design of Mineralocorticoid Receptor Antagonists to Explore Oxosteroid Receptor Selectivity
ChemMedChem·2016· 14 cited
Fragment Screening of RORγt Using Cocktail Crystallography: Identification of Simultaneous Binding of Multiple Fragments
ChemMedChem·2016· 9 cited
Fragment Screening of Soluble Epoxide Hydrolase for Lead Generation—Structure‐Based Hit Evaluation and Chemistry Exploration
ChemMedChem·2016· 15 cited
Back Cover: Benzoxazepines Achieve Potent Suppression of IL‐17 Release in Human T‐Helper 17 (T<sub>H</sub>17) Cells through an Induced‐Fit Binding Mode to the Nuclear Receptor RORγ (ChemMedChem 2/2016)
ChemMedChem·2016Open Access
Benzoxazepines Achieve Potent Suppression of IL‐17 Release in Human T‐Helper 17 (T<sub>H</sub>17) Cells through an Induced‐Fit Binding Mode to the Nuclear Receptor RORγ
ChemMedChem·2015· 61 cited
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Frequent Co-authors

Stefan von Berg(7), Anna Aagaard(7), Anders Liljas(5), Linda Öster(5), Eva Hansson(5), William N. Lipscomb(4), Stephen Hanessian(4), Roine I. Olsson(4), Jane McPheat(4), Johan Jirholt(4), Rongfeng Chen(4), Yao Xiong(4), T. Hansson(4), Frank Narjes(4), Kjell Erik Julius Håkansson(3), Shenghua Huang(3), Sven Lindskog(3), Bengt‐Harald Jonsson(3), Johanna Deinum(3), Tomas Fex(3)