Roine I. Olsson

AstraZeneca (Sweden) — Sweden

Immunology and Microbiology · Life Sciences

10h-index332citations12works0.02yr avg
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Research Topics

Psoriasis: Treatment and Pathogenesis(5), T-cell and B-cell Immunology(2), Neurotransmitter Receptor Influence on Behavior(2), Cannabis and Cannabinoid Research(2), Inflammatory mediators and NSAID effects(2)

Publications12 total

AZD0284, a Potent, Selective, and Orally Bioavailable Inverse Agonist of Retinoic Acid Receptor-Related Orphan Receptor C2
Journal of Medicinal Chemistry·2021· 24 citedOpen Access
Discovery of Potent and Orally Bioavailable Inverse Agonists of the Retinoic Acid Receptor-Related Orphan Receptor C2
ACS Medicinal Chemistry Letters·2019· 18 cited
Potent and Orally Bioavailable Inverse Agonists of RORγt Resulting from Structure-Based Design
Journal of Medicinal Chemistry·2018· 37 citedOpen Access
Discovery of a Novel Oral Glucocorticoid Receptor Modulator (AZD9567) with Improved Side Effect Profile
Journal of Medicinal Chemistry·2018· 73 citedOpen Access
Structure–Affinity Relationships and Structure–Kinetic Relationships of 1,2-Diarylimidazol-4-carboxamide Derivatives as Human Cannabinoid 1 Receptor Antagonists
Journal of Medicinal Chemistry·2017· 9 citedOpen Access
Isoindolinone compounds active as Kv1.5 blockers identified using a multicomponent reaction approach
Bioorganic & Medicinal Chemistry Letters·2016· 23 citedOpen Access
Back Cover: Benzoxazepines Achieve Potent Suppression of IL‐17 Release in Human T‐Helper 17 (T<sub>H</sub>17) Cells through an Induced‐Fit Binding Mode to the Nuclear Receptor RORγ (ChemMedChem 2/2016)
ChemMedChem·2016Open Access
Benzoxazepines Achieve Potent Suppression of IL‐17 Release in Human T‐Helper 17 (T<sub>H</sub>17) Cells through an Induced‐Fit Binding Mode to the Nuclear Receptor RORγ
ChemMedChem·2015· 61 cited
Lactam sulfonamides as potent inhibitors of the Kv1.5 potassium ion channel
Bioorganic & Medicinal Chemistry Letters·2014· 10 citedOpen Access
Synthesis and evaluation of diphenylphosphinic amides and diphenylphosphine oxides as inhibitors of Kv1.5
Bioorganic & Medicinal Chemistry Letters·2012· 30 citedOpen Access
Novel thioamide derivatives as neutral CB1 receptor antagonists
Bioorganic & Medicinal Chemistry Letters·2009· 27 citedOpen Access
Composition of the activated complex in the stereoselective deprotonation of cyclohexene oxide by a chiral lithium amide
Tetrahedron Asymmetry·1999· 20 cited

Frequent Co-authors

Jesper Malmberg(6), Yafeng Xue(5), Stefan von Berg(5), Anna Aagaard(5), Jane McPheat(5), Eva Hansson(5), Johan Jirholt(5), Rongfeng Chen(5), Yao Xiong(5), T. Hansson(5), Frank Narjes(5), Matti Lepistö(4), Hanna Grindebacke(4), Agnes Leffler(4), Hongbin Ge(3), Antonio Llinàs(3), Ingemar Jacobson(3), Jonas Boström(3), Annika Björe(3), Johan Sundell(3)