Muriel Eaton

Purdue University West Lafayette — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

9h-index364citations20works19.02yr avg
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Research Topics

Ion channel regulation and function(5), Neuroscience and Neuropharmacology Research(4), Autism Spectrum Disorder Research(4), Genetics and Neurodevelopmental Disorders(4), Pain Mechanisms and Treatments(3)

Publications20 total

Single-nucleus transcriptomics reveal disrupted pathways in the prefrontal cortex of <i>Scn2a</i> -deficient mice
2025· 1 citedOpen Access
Restoration of excitation/inhibition balance enhances neuronal signal-to-noise ratio and rescues social deficits in autism-associated <i>Scn2a</i> -deficiency
2025· 8 cited
Microglial over-pruning of synapses during development in autism-associated SCN2A-deficient mice and human cerebral organoids
Molecular Psychiatry·2024· 48 cited
Microglial over-pruning of synapses during development in autism-associated SCN2A-deficient mice and human cerebral organoids
2023· 13 citedOpen Access
Deficiency of autism-related Scn2a gene in mice disrupts sleep patterns and circadian rhythms
Neurobiology of Disease·2022· 32 citedOpen Access
Hyperexcitability and Pharmacological Responsiveness of Cortical Neurons Derived from Human iPSCs Carrying Epilepsy-Associated Sodium Channel Nav1.2-L1342P Genetic Variant
Journal of Neuroscience·2021· 47 citedOpen Access
Severe deficiency of the voltage-gated sodium channel NaV1.2 elevates neuronal excitability in adult mice
Cell Reports·2021· 117 citedOpen Access
Multi-Electrode Array of Sensory Neurons as an In Vitro Platform to Identify the Nociceptive Response to Pharmaceutical Buffer Systems of Injectable Biologics
Pharmaceutical Research·2021· 10 cited
Severe deficiency of voltage-gated sodium channel Na <sub>V</sub> 1.2 elevates neuronal excitability in adult mice
2021· 2 citedOpen Access
Sodium channel Nav1.2-L1342P variant displaying complex biophysical properties renders hyperexcitability of cortical neurons derived from human iPSCs
2021· 3 citedOpen Access
Generation and basic characterization of a gene‐trap knockout mouse model of <i>Scn2a</i> with a substantial reduction of voltage‐gated sodium channel Na<sub>v</sub>1.2 expression
Genes Brain & Behavior·2020· 39 citedOpen Access
Examining Sodium and Potassium Channel Conductances Involved in Hyperexcitability of Chemotherapy-Induced Peripheral Neuropathy: A Mathematical and Cell Culture-Based Study
Frontiers in Computational Neuroscience·2020· 18 citedOpen Access
Faculty Opinions recommendation of CaMKII enhances voltage-gated sodium channel Nav1.6 activity and neuronal excitability.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2020
Characterization of a gene-trap knockout mouse model of <i>Scn2a</i> encoding voltage-gated sodium channel Nav1.2
2020· 1 citedOpen Access
A mathematical investigation of chemotherapy-induced peripheral neuropathy
2020· 1 citedOpen Access
Faculty Opinions recommendation of Synthesis of a Fluorescent Analogue of Paclitaxel That Selectively Binds Microtubules and Sensitively Detects Efflux by P-Glycoprotein.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2018
Faculty Opinions recommendation of FGF13 Selectively Regulates Heat Nociception by Interacting with Nav1.7.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2018
CRISPR-UnLOCK: Multipurpose Cas9-Based Strategies for Conversion of Yeast Libraries and Strains
Frontiers in Microbiology·2017· 24 citedOpen Access
A Model Interaction for Structural Biology and Health Research: Implications of the Antibody D25 bound to the RSV Pre‐Fusion Glycoprotein (LB100)
The FASEB Journal·2014
AGGREGATED PROTEINS? LET's PUT A CAP ON THAT! Exploration of the GroEL‐GroES‐(ADP) <sub>7</sub> Chaperonin Complex
The FASEB Journal·2013

Frequent Co-authors

Yang Yang(13), Jingliang Zhang(12), Zhefu Que(10), Xiaoling Chen(9), Tiange Xiao(8), Jiaxiang Wu(7), William C. Skarnes(7), Maria I. Olivero-Acosta(6), Zhuo Huang(6), Zhixiong Ma(5), Chris Yuan(5), Nadia A. Lanman(5), Kyle Wettschurack(5), Manasi Halurkar(4), Wendy A. Koss(4), Ji Hea Lee(3), James A. Schaber(3), Yuanrui Zhao(3), Zaiyang Zhang(3), Yang Yang(3)