Tiange Xiao

Purdue University West Lafayette — United States

Neuroscience · Life Sciences

7h-index302citations19works8.12yr avg
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Research Topics

Neurotransmitter Receptor Influence on Behavior(5), Neuroscience and Neuropharmacology Research(4), Ion channel regulation and function(4), Neuroinflammation and Neurodegeneration Mechanisms(4), Genetics and Neurodevelopmental Disorders(4)

Publications19 total

Disrupted theta synchronization and synaptic connectivity in the visual cortex of Fmr1 KO mice
Nature Communications·2025Open Access
Restoration of excitation/inhibition balance enhances neuronal signal-to-noise ratio and rescues social deficits in autism-associated <i>Scn2a</i> -deficiency
2025· 8 cited
Escalation of intravenous fentanyl self-administration and assessment of withdrawal behavior in male and female mice
Psychopharmacology·2024· 3 cited
Human IPSC-Derived Microglia Sense and Dampen Hyperexcitability of Cortical Neurons Carrying the Epilepsy-Associated<i>SCN2A</i>-L1342P Mutation
Journal of Neuroscience·2024· 9 citedOpen Access
Temporal differential effects of post-injury alcohol consumption in a mouse model of blast-induced traumatic brain injury
Neuroscience·2024· 3 citedOpen Access
Impaired Experience-Dependent Theta Oscillation Synchronization and Inter-Areal Synaptic Connectivity in the Visual Cortex of Fmr1 KO Mice
2024· 1 citedOpen Access
Escalation of intravenous fentanyl self-administration and assessment of withdrawal behavior in male and female mice
2024Open Access
Microglial over-pruning of synapses during development in autism-associated SCN2A-deficient mice and human cerebral organoids
Molecular Psychiatry·2024· 48 cited
A role for circuitry of the cortical amygdala in excessive alcohol drinking, withdrawal, and alcohol use disorder
Alcohol·2024· 1 citedOpen Access
Human iPSC-derived microglia sense and dampen hyperexcitability of cortical neurons carrying the epilepsy-associated SCN2A-L1342P mutation
2023· 4 citedOpen Access
Microglial over-pruning of synapses during development in autism-associated SCN2A-deficient mice and human cerebral organoids
2023· 13 citedOpen Access
Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder
Journal of Visualized Experiments·2023· 4 citedOpen Access
Prior experience with flavored alcohol increases preference for flavored alcohol but flavor does not influence binge-like drinking behavior in mice
Physiology & Behavior·2023· 2 citedOpen Access
Flavored Alcohol Increases Alcohol Preference But Does Not Influence Binge-Like Drinking Behavior in Mice
SSRN Electronic Journal·2023Open Access
Hyperexcitability and Pharmacological Responsiveness of Cortical Neurons Derived from Human iPSCs Carrying Epilepsy-Associated Sodium Channel Nav1.2-L1342P Genetic Variant
Journal of Neuroscience·2021· 47 citedOpen Access
Severe deficiency of the voltage-gated sodium channel NaV1.2 elevates neuronal excitability in adult mice
Cell Reports·2021· 117 citedOpen Access
Severe deficiency of voltage-gated sodium channel Na <sub>V</sub> 1.2 elevates neuronal excitability in adult mice
2021· 2 citedOpen Access
Generation and basic characterization of a gene‐trap knockout mouse model of <i>Scn2a</i> with a substantial reduction of voltage‐gated sodium channel Na<sub>v</sub>1.2 expression
Genes Brain & Behavior·2020· 39 citedOpen Access
Characterization of a gene-trap knockout mouse model of <i>Scn2a</i> encoding voltage-gated sodium channel Nav1.2
2020· 1 citedOpen Access

Frequent Co-authors

Jingliang Zhang(10), Xiaoling Chen(10), Yang Yang(10), Jiaxiang Wu(9), Zhefu Que(9), Adam Kimbrough(9), Muriel Eaton(8), William C. Skarnes(8), Maria I. Olivero-Acosta(7), Chris Yuan(6), Kyle Wettschurack(6), Yueyi Chen(6), Zhuo Huang(5), Yuanrui Zhao(5), Manasi Halurkar(5), Zhixiong Ma(4), Ningren Cui(4), Ian Chen(4), Ranjie Xu(4), Wendy A. Koss(4)