Manching Ku

Salk Institute for Biological Studies — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

33h-index20.9kcitations71works3.32yr avg
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Research Topics

Genomics and Chromatin Dynamics(14), Epigenetics and DNA Methylation(13), Cutaneous Melanoma Detection and Management(12), Melanoma and MAPK Pathways(12), Pluripotent Stem Cells Research(11)

Publications70 total

Characterisation of an autochthonous mouse ccRCC model of immune checkpoint inhibitor therapy resistance
Scientific Reports·2025· 2 citedOpen Access
TGF-β signaling redirects Sox11 gene regulatory activity to promote partial EMT and collective invasion of oncogenically transformed intestinal organoids
Oncogenesis·2025· 3 citedOpen Access
Dynamic WNT signaling controls differentiation of hematopoietic progenitor cells from human pluripotent stem cells
Science China Life Sciences·2025· 2 citedOpen Access
Integrative metabolomics-genomics analysis identifies key networks in a stem cell-based model of schizophrenia
Molecular Psychiatry·2024· 6 citedOpen Access
Integrative metabolomics-genomics analysis identifies key networks in a stem cell-based model of schizophrenia.
Research Square (Research Square)·2022Open Access
Author Correction: Wiskott-Aldrich syndrome protein forms nuclear condensates and regulates alternative splicing
Nature Communications·2022Open Access
Wiskott-Aldrich syndrome protein forms nuclear condensates and regulates alternative splicing
Nature Communications·2022· 19 citedOpen Access
Exhaustion of CD39-Expressing CD8+ T Cells in Crohn’s Disease Is Linked to Clinical Outcome
Gastroenterology·2022· 25 cited
Spatially resolved multi-omics deciphers bidirectional tumor-host interdependence in glioblastoma
Cancer Cell·2022· 571 citedOpen Access
Dynamic transcriptome analysis reveals signatures of paradoxical effect of vemurafenib on human dermal fibroblasts
Cell Communication and Signaling·2021· 9 citedOpen Access
Publisher Correction: Clinical evolution, genetic landscape and trajectories of clonal hematopoiesis in SAMD9/SAMD9L syndromes
Nature Medicine·2021· 4 citedOpen Access
Clinical evolution, genetic landscape and trajectories of clonal hematopoiesis in SAMD9/SAMD9L syndromes
Nature Medicine·2021· 161 citedOpen Access
Abstract 3122: Negative correlation of single-cell PAX3:FOXO1 expression with tumorigenicity in rhabdomyosarcoma
Cancer Research·2021
Negative correlation of single-cell <i>PAX3:FOXO1</i> expression with tumorigenicity in rhabdomyosarcoma
Life Science Alliance·2021· 14 citedOpen Access
Age-dependent instability of mature neuronal fate in induced neurons from Alzheimer’s patients
Cell stem cell·2021· 233 citedOpen Access
Additional file 10 of Dynamic transcriptome analysis reveals signatures of paradoxical effect of vemurafenib on human dermal fibroblasts
Figshare·2021Open Access
Additional file 9 of Dynamic transcriptome analysis reveals signatures of paradoxical effect of vemurafenib on human dermal fibroblasts
Figshare·2021Open Access
Additional file 7 of Dynamic transcriptome analysis reveals signatures of paradoxical effect of vemurafenib on human dermal fibroblasts
Figshare·2021Open Access
Additional file 5 of Dynamic transcriptome analysis reveals signatures of paradoxical effect of vemurafenib on human dermal fibroblasts
Figshare·2021Open Access
Additional file 6 of Dynamic transcriptome analysis reveals signatures of paradoxical effect of vemurafenib on human dermal fibroblasts
Figshare·2021Open Access
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Frequent Co-authors

B Bernstein(17), Fred H. Gage(8), Jérôme Mertens(7), Apuã C.M. Paquola(7), Melanie Boerries(7), Richard P. Koche(6), Tarjei S. Mikkelsen(5), Alexander Meissner(5), Eric S. Lander(5), Hyungjun Lee(5), Joseph R. Herdy(5), Yi Yang(5), Kathy O. Lui(5), Eric M. Mendenhall(4), Marius Wernig(4), Rudolf Jaenisch(4), Yongsung Kim(4), Marie Follo(4), Simon T. Schafer(4), Jan Starý(4)