Martijn Gloerich

Utrecht University — Netherlands

Biochemistry, Genetics and Molecular Biology · Life Sciences

26h-index2.2kcitations55works8.92yr avg
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Research Topics

Hippo pathway signaling and YAP/TAZ(25), Cellular Mechanics and Interactions(18), Cancer Cells and Metastasis(11), Wnt/β-catenin signaling in development and cancer(9), Prostate Cancer Treatment and Research(8)

Publications55 total

β-catenin condensation facilitates clustering of the cadherin/catenin complex and formation of nascent cell-cell junctions
Nature Communications·2025Open Access
Self-organization of tumor heterogeneity and plasticity
2025Open Access
Mechanosensitive calcium channels and integrins coordinate the reprogramming of colorectal cancer cells into a fetal-like state
Cell Reports·2025· 2 citedOpen Access
β-Catenin condensation facilitates clustering of the cadherin/catenin complex and formation of nascent cell-cell junctions
2025Open Access
Intestinal tuft cell subtypes represent successive stages of maturation driven by crypt-villus signaling gradients
Nature Communications·2025· 2 citedOpen Access
Mechanical Coordination of Intestinal Cell Extrusion by Supracellular 3D Force Patterns
2025Open Access
E-cadherin mechanotransduction activates EGFR-ERK signaling in epithelial monolayers by inducing ADAM-mediated ligand shedding
Science Signaling·2025· 4 cited
Integrin-TGFβ axis induces partial EMT in basal-like cells to lead collective invasion
2025
Tumour-intrinsic alterations and stromal matrix remodelling promote Wnt-niche independence during diffuse-type gastric cancer progression
Gut·2025· 2 citedOpen Access
E-cadherin mechanotransduction activates EGFR-ERK signaling in epithelial cells by inducing ADAM-mediated ligand shedding
2025
Mature tuft cell phenotypes are sequentially expressed along the intestinal crypt-villus axis following cytokine-induced tuft cell hyperplasia
2024· 2 citedOpen Access
PIEZO-dependent mechanosensing is essential for intestinal stem cell fate decision and maintenance
Science·2024· 74 citedOpen Access
PIEZO-dependent mechano-sensing of the niche is essential for intestinal stem cell fate decision and maintenance
2024Open Access
A YAP-centered mechanotransduction loop drives collective breast cancer cell invasion
Nature Communications·2024· 36 citedOpen Access
Cell division‐dependent dissemination following E‐cadherin loss underlies initiation of diffuse‐type gastric cancer
The Journal of Pathology·2024· 11 citedOpen Access
Mechanical regulation of cell fate transitions underlying colorectal cancer metastasis formation
2023· 3 citedOpen Access
Co-cultures of colon cancer cells and cancer-associated fibroblasts recapitulate the aggressive features of mesenchymal-like colon cancer
Frontiers in Immunology·2023· 91 citedOpen Access
Supplementary Data from Liver Colonization by Colorectal Cancer Metastases Requires YAP-Controlled Plasticity at the Micrometastatic Stage
2023Open Access
Supplementary Data from Liver Colonization by Colorectal Cancer Metastases Requires YAP-Controlled Plasticity at the Micrometastatic Stage
2023Open Access
Supplementary Data from Liver Colonization by Colorectal Cancer Metastases Requires YAP-Controlled Plasticity at the Micrometastatic Stage
2023Open Access
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Frequent Co-authors

Hugo J.G. Snippert(14), Jacco van Rheenen(14), Mirjam C. van der Net(13), Joris H. Hageman(12), Onno Kranenburg(12), Marjolein J. Vliem(11), Maria C. Heinz(11), Ingrid Verlaan-Klink(11), Niek A. Peters(10), Ronja M. Houtekamer(10), Koen C. Oost(9), Rik G.H. Lindeboom(9), Lisa van Voorthuijsen(9), Arianna Fumagalli(9), Gustavo de Medeiros(9), Inne H.M. Borel Rinkes(9), Prisca Liberali(9), Michiel Vermeulen(9), Willem‐Jan Pannekoek(9), Johannes L. Bos(8)