David P. Bartel

Howard Hughes Medical Institute — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

121h-index195.6kcitations315works6.22yr avg
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Research Topics

RNA Research and Splicing(106), RNA and protein synthesis mechanisms(95), MicroRNA in disease regulation(94), RNA modifications and cancer(56), RNA Interference and Gene Delivery(47)

Publications314 total

The G3BP stress-granule proteins reinforce the integrated stress response translation programme
Nature Cell Biology·2025· 2 citedOpen Access
mRNA 3′ UTRs direct microRNA degradation to participate in imprinted gene networks and regulate growth
2025Open Access
Functional microRNA targeting without seed pairing
Nucleic Acids Research·2025· 2 citedOpen Access
mRNA poly(A)-tail length is a battleground for coronavirus–host competition
2025· 2 citedOpen Access
Lysosomal RNA profiling reveals targeting of specific types of RNAs for degradation
2025· 2 citedOpen Access
PAL-AI reveals genetic determinants that control poly(A)-tail length during oocyte maturation, with relevance to human fertility
Nature Communications·2025Open Access
Global inhibition of deadenylation stabilizes the transcriptome in mitotic cells
2025· 1 citedOpen Access
Polyglycine-mediated aggregation of FAM98B disrupts tRNA processing in GGC repeat disorders
Science·2025· 5 cited
5′ untranslated regions tune <i>Toxoplasma</i> translation
2025Open Access
Derepression of a single microRNA target causes female infertility in mice
2025· 1 citedOpen Access
Functional microRNA targeting without seed pairing
2025· 4 citedOpen Access
The structural basis for RNA slicing by human Argonaute2
Cell Reports·2024· 17 citedOpen Access
PAL-AI reveals genetic determinants that control poly(A)-tail length during oocyte maturation, with relevance to human fertility
2024Open Access
Nuclear release of eIF1 restricts start-codon selection during mitosis
Nature·2024· 23 citedOpen Access
Widespread destabilization of <i>Caenorhabditis elegans</i> microRNAs by the E3 ubiquitin ligase EBAX-1
RNA·2024· 11 citedOpen Access
The G3BP stress-granule proteins reinforce the integrated-stress-response translation program
2024· 7 citedOpen Access
The structural basis for RNA slicing by human Argonaute2
2024· 1 citedOpen Access
The guide-RNA sequence dictates the slicing kinetics and conformational dynamics of the Argonaute silencing complex
Molecular Cell·2024· 18 citedOpen Access
Widespread destabilization of <i>C. elegans</i> microRNAs by the E3 ubiquitin ligase EBAX-1
2024· 1 citedOpen Access
Nuclear release of eIF1 globally increases stringency of start-codon selection to preserve mitotic arrest physiology
2024· 7 citedOpen Access
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Frequent Co-authors

Christopher B. Burge(8), Lee P. Lim(7), Bonnie Bartel(6), Nelson C. Lau(4), Andrew Grimson(4), Wendy K. Johnston(4), Phillip D. Zamore(4), Hervé Vaucheret(4), Benjamin P. Lewis(3), Kyle Kai‐How Farh(3), George W. Bell(3), Matthew W. Jones-Rhoades(3), Daehyun Baek(3), Chanseok Shin(3), Earl G. Weinstein(3), Thomas Tuschl(3), Phillip A. Sharp(3), Matthew W. Rhoades(3), Brenda J. Reinhart(3), Soraya Yekta(3)