Ling Xu

Sanofi (United States) — United States

Immunology and Microbiology · Life Sciences

36h-index9.5kcitations46works0.02yr avg
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Research Topics

HIV Research and Treatment(29), Immune Cell Function and Interaction(17), Viral Infections and Outbreaks Research(10), Virus-based gene therapy research(9), Hepatitis B Virus Studies(7)

Publications46 total

Potent anti-viral activity of a trispecific HIV neutralizing antibody in SHIV-infected monkeys
Cell Reports·2022· 30 citedOpen Access
Roles of Toll-like Receptor 3 in Intrauterine Transmission of Hepatitis B Virus in Mothers with High Viral Load
Diseases & Research·2021Open Access
Trispecific broadly neutralizing HIV antibodies mediate potent SHIV protection in macaques
Science·2017· 266 citedOpen Access
Broadly Neutralizing Human Immunodeficiency Virus Type 1 Antibody Gene Transfer Protects Nonhuman Primates from Mucosal Simian-Human Immunodeficiency Virus Infection
Journal of Virology·2015· 121 citedOpen Access
Outer Domain of HIV-1 gp120: Antigenic Optimization, Structural Malleability, and Crystal Structure with Antibody VRC-PG04
Journal of Virology·2012· 36 citedOpen Access
Mammalian production of an isotopically enriched outer domain of the HIV-1 gp120 glycoprotein for NMR spectroscopy
Journal of Biomolecular NMR·2011· 21 citedOpen Access
147 Rational Design of Envelope Surface Identifies Broadly Neutralizing Human Monoclonal Antibodies to HIV-1
JAIDS Journal of Acquired Immune Deficiency Syndromes·2011· 1 cited
Induction of Broadly Neutralizing H1N1 Influenza Antibodies by Vaccination
Science·2010· 340 cited
Rational Design of Envelope Identifies Broadly Neutralizing Human Monoclonal Antibodies to HIV-1
Science·2010· 1.8k cited
Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01
Science·2010· 1.2k cited
Structural Basis of Immune Evasion at the Site of CD4 Attachment on HIV-1 gp120
Science·2009· 298 citedOpen Access
Different Vaccine Vectors Delivering the Same Antigen Elicit CD8+ T Cell Responses with Distinct Clonotype and Epitope Specificity
The Journal of Immunology·2009· 29 citedOpen Access
Structure-Based Stabilization of HIV-1 gp120 Enhances Humoral Immune Responses to the Induced Co-Receptor Binding Site
PLoS Pathogens·2009· 118 citedOpen Access
Enhanced Exposure of the CD4-Binding Site to Neutralizing Antibodies by Structural Design of a Membrane-Anchored Human Immunodeficiency Virus Type 1 gp120 Domain
Journal of Virology·2009· 48 citedOpen Access
Comparative Efficacy of Neutralizing Antibodies Elicited by Recombinant Hemagglutinin Proteins from Avian H5N1 Influenza Virus
Journal of Virology·2008· 146 citedOpen Access
Immunization by Avian H5 Influenza Hemagglutinin Mutants with Altered Receptor Binding Specificity
Science·2007· 255 citedOpen Access
Structural definition of a conserved neutralization epitope on HIV-1 gp120
Nature·2007· 760 citedOpen Access
Efficient protein boosting after plasmid DNA or recombinant adenovirus immunization with HIV-1 vaccine constructs
Vaccine·2006· 77 citedOpen Access
Virus-Specific Cellular Immune Correlates of Survival in Vaccinated Monkeys after Simian Immunodeficiency Virus Challenge
Journal of Virology·2006· 61 citedOpen Access
Protective immunity to lethal challenge of the 1918 pandemic influenza virus by vaccination
Proceedings of the National Academy of Sciences·2006· 80 citedOpen Access
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Frequent Co-authors

Gary J. Nabel(44), Zhi-Yong Yang(24), John R. Mascola(23), Wing-Pui Kong(15), Bimal K. Chakrabarti(12), Peter D. Kwong(11), Tongqing Zhou(10), Norman L. Letvin(10), Zhiyong Yang(7), Michael S. Seaman(6), Mark K. Louder(6), Mario Roederer(6), Sampa Santra(6), Xueling Wu(5), Stephen D. Schmidt(5), Sijy O’Dell(5), Richard T. Wyatt(5), Richard A. Koup(5), Darci A. Gorgone(5), Srinivas S. Rao(5)