Michael Tieu

Allen Institute for Brain Science — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

31h-index11.3kcitations56works26.22yr avg
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Research Topics

Single-cell and spatial transcriptomics(32), Neuroinflammation and Neurodegeneration Mechanisms(28), Neural dynamics and brain function(14), Neurogenesis and neuroplasticity mechanisms(8), Neuroscience and Neuropharmacology Research(6)

Publications49 total

Cross-species consensus atlas of the primate basal ganglia
2025· 5 citedOpen Access
Multimodal Atlas of Caudate Head Reveals Impact of pTau Burden on Resident Glial Cells
Alzheimer s & Dementia·2025Open Access
An integrated, multiregional, and multimodal cell atlas of Alzheimer’s disease
Alzheimer s & Dementia·2025Open Access
Enhancer-AAVs allow genetic access to oligodendrocytes and diverse populations of astrocytes across species
2025· 1 citedOpen Access
Enhancer-AAVs allow genetic access to oligodendrocytes and diverse populations of astrocytes across species
2025Open Access
Distinctive physiology of molecularly identified medium spiny neurons in the macaque putamen
Cell Reports·2024· 1 citedOpen Access
Integrated multimodal cell atlas of Alzheimer’s disease
Nature Neuroscience·2024· 201 citedOpen Access
Areal specializations in the morpho-electric and transcriptomic properties of primate layer 5 extratelencephalic projection neurons
Cell Reports·2024· 9 citedOpen Access
A suite of enhancer AAVs and transgenic mouse lines for genetic access to cortical cell types
2024· 21 citedOpen Access
A high-resolution transcriptomic and spatial atlas of cell types in the whole mouse brain
Nature·2023· 892 citedOpen Access
Connecting single-cell transcriptomes to projectomes in mouse visual cortex
2023· 13 citedOpen Access
Signature morphoelectric properties of diverse GABAergic interneurons in the human neocortex
Science·2023· 114 citedOpen Access
Comparative transcriptomics reveals human-specific cortical features
Science·2023· 171 citedOpen Access
Transcriptomic cytoarchitecture reveals principles of human neocortex organization
Science·2023· 173 citedOpen Access
Morphoelectric and transcriptomic divergence of the layer 1 interneuron repertoire in human versus mouse neocortex
Science·2023· 78 citedOpen Access
Enhancer-AAVs allow genetic access to oligodendrocytes and diverse populations of astrocytes across species
2023· 24 citedOpen Access
Integrated multimodal cell atlas of Alzheimer’s disease
2023· 63 citedOpen Access
Integrated multimodal cell atlas of Alzheimer’s disease
2023· 40 citedOpen Access
A high-resolution transcriptomic and spatial atlas of cell types in the whole mouse brain
2023· 135 citedOpen Access
Signature morpho-electric properties of diverse GABAergic interneurons in the human neocortex
2022· 22 citedOpen Access
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Frequent Co-authors

Jeff Goldy(44), Kimberly A. Smith(42), Darren Bertagnolli(38), Nick Dee(37), Tamara Casper(35), Delissa McMillen(33), Christine Rimorin(31), Ed S. Lein(30), Bosiljka Tasic(26), Zizhen Yao(26), Hongkui Zeng(26), Trygve E. Bakken(24), Amy Torkelson(24), Susan M. Sunkin(23), Matthew Kroll(21), Boaz P. Levi(21), Rachel Dalley(21), Augustin Ruiz(21), C. Dirk Keene(20), Jonathan T. Ting(20)