Tae Kwang Ha

Novo Nordisk Foundation — Denmark

Biochemistry, Genetics and Molecular Biology · Life Sciences

17h-index822citations25works0.02yr avg
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Research Topics

Viral Infectious Diseases and Gene Expression in Insects(21), Protein purification and stability(10), Virus-based gene therapy research(7), CRISPR and Genetic Engineering(6), RNA Interference and Gene Delivery(3)

Publications25 total

Enhancing CHO cell productivity through a dual selection system using Aspg and Gs in glutamine free medium
Biotechnology and Bioengineering·2022· 13 cited
Enhancing CHO cell productivity through a dual selection system using Aspg and Gs in glutamine free medium
2022· 1 citedOpen Access
Factors affecting the quality of therapeutic proteins in recombinant Chinese hamster ovary cell culture
Biotechnology Advances·2021· 61 cited
Knockout of sialidase and pro-apoptotic genes in Chinese hamster ovary cells enables the production of recombinant human erythropoietin in fed-batch cultures
Metabolic Engineering·2019· 27 cited
Platform Technology for Therapeutic Protein Production
2019· 6 cited
Reprogramming AA catabolism in CHO cells with CRISPR/Cas9 genome editing improves cell growth and reduces byproduct secretion
Metabolic Engineering·2019· 32 citedOpen Access
BiP Inducer X: An ER Stress Inhibitor for Enhancing Recombinant Antibody Production in CHO Cell Culture
Biotechnology Journal·2019· 24 citedOpen Access
Revealing Key Determinants of Clonal Variation in Transgene Expression in Recombinant CHO Cells Using Targeted Genome Editing
ACS Synthetic Biology·2018· 45 citedOpen Access
2,6-Dimethoxy-1,4-benzoquinone Inhibits 3T3-L1 Adipocyte Differentiation via Regulation of AMPK and mTORC1
Planta Medica·2018· 8 cited
Baicalein Reduces Oxidative Stress in CHO Cell Cultures and Improves Recombinant Antibody Productivity
Biotechnology Journal·2017· 32 citedOpen Access
Ribosome profiling-guided depletion of an mRNA increases cell growth rate and protein secretion
Scientific Reports·2017· 60 citedOpen Access
Combinatorial treatment with lithium chloride enhances recombinant antibody production in transiently transfected CHO and HEK293E cells
Biotechnology and Bioprocess Engineering·2016· 5 cited
Glutamine substitution: the role it can play to enhance therapeutic protein production
Pharmaceutical Bioprocessing·2015· 9 citedOpen Access
Understanding of altered <i>N</i>‐glycosylation‐related gene expression in recombinant Chinese hamster ovary cells subjected to elevated ammonium concentration by digital mRNA counting
Biotechnology and Bioengineering·2015· 31 cited
Ethanolic Extract of Taheebo Attenuates Increase in Body Weight and Fatty Liver in Mice Fed a High-Fat Diet
Molecules·2014· 17 citedOpen Access
Effect of lithium chloride on the production and sialylation of Fc-fusion protein in Chinese hamster ovary cell culture
Applied Microbiology and Biotechnology·2014· 32 cited
Effect of glutamine substitution by TCA cycle intermediates on the production and sialylation of Fc-fusion protein in Chinese hamster ovary cell culture
Journal of Biotechnology·2014· 49 cited
Effect of Bcl‐x<sub>L</sub> overexpression on lactate metabolism in chinese hamster ovary cells producing antibody
Biotechnology Progress·2013· 2 cited
Anti‐cell death engineering of CHO cells: Co‐overexpression of Bcl‐2 for apoptosis inhibition, Beclin‐1 for autophagy induction
Biotechnology and Bioengineering·2013· 53 citedOpen Access
Current state and perspectives on erythropoietin production
Applied Microbiology and Biotechnology·2012· 30 cited
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Frequent Co-authors

Gyun Min Lee(18), Helene Faustrup Kildegaard(8), Jae Seong Lee(5), Che Lin Kim(3), Lise Marie Grav(3), Nathan E. Lewis(3), Yeon‐Gu Kim(3), Hooman Hefzi(3), Anders Holmgaard Hansen(3), Lasse Ebdrup Pedersen(2), Daniel Ley(2), Mikael Rørdam Andersen(2), Jin Hyoung Park(2), Young Kue Han(2), Jiyun Ahn(2), Chang Wook Jung(2), Andreu Òdena(2), Karen Julie la Cour Karottki(2), Lars K. Nielsen(2), Antje Müller(1)